Sugi Predict

Sugi Predict / Compounds / SCHEMBL50344

SCHEMBL50344

SCHEMBL50344

O=C(c1ccccc1)C(O)(N=NC(O)(C(=O)c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES1 P23141 5/20 0.48
▸ SRC P12931 1/20 0.44
▸ CES2 O00748 2/20 0.41
▸ TSHR P16473 2/20 0.41
▸ DAO P14920 1/20 0.41
▸ NAPRT Q6XQN6 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ CYP1A2 P05177 1/20 0.39
▸ MAPT P10636 3/20 0.38
▸ CYP3A4 P08684 2/20 0.38
▸ TDP1 Q9NUW8 2/20 0.38
▸ CA2 P00918 2/20 0.38
▸ CA4 P22748 2/20 0.38
▸ POLB P06746 1/20 0.38
▸ PARP1 P09874 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ RECQL P46063 1/20 0.38
▸ BLM P54132 1/20 0.38
▸ PMP22 Q01453 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18669365 0.86 CES1 (0.47) CES1SRCCES2TSHRDAO
SCHEMBL11560426 0.84 CES1 (0.41) CES1SRCTSHRALDH1A1CYP1A2
SCHEMBL9941263 0.82 CES1 (0.38) CES1SRCCES2TSHRDAO
SCHEMBL11431031 0.81 CES1 (0.43) CES1SRCCES2TSHRDAO
SCHEMBL1079930 0.80 CES1 (0.54) CES1SRCCES2TSHRDAO
SCHEMBL680607 0.78 CES1 (0.57) CES1SRCCES2TSHRDAO
SCHEMBL1168769 0.77 CES1 (0.50) CES1SRCCES2TSHRDAO
SCHEMBL242506 0.76 CES1 (0.54) CES1SRCCES2TSHRDAO
SCHEMBL562162 0.76 CES1 (0.54) CES1SRCCES2TSHRDAO
SCHEMBL252920 0.76 CES1 (0.54) CES1SRCCES2TSHRDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871831-B2 Modification of surfaces with polymers University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2014-10-28 — — US claimed
US-20140058032-A1 MODIFICATION OF SURFACES WITH POLYMERS CARNEGIE MELLON UNIVERSITY 2014-02-27 — — US claimed
US-20130131278-A1 MODIFICATION OF SURFACES WITH POLYMERS NATIONAL SCIENCE FOUNDATION 2013-05-23 — — US claimed
US-20130058910-A1 DECONTAMINATION OF CHEMICAL AND BIOLOGICAL AGENTS PITTSBURGH, UNIVERSITY OF - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2013-03-07 — — US claimed
US-8349410-B2 Modification of surfaces with polymers University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2013-01-08 — — US claimed
US-20080139689-A1 Controlled free radical polymerization, crosslinking, Norrish reaction; segments can be hydrophilicity, hydrophobicity, biocompatibility, bioactivity, adhesion, adsorption; corrosion, abrasion and, heat resistance; dielectrics; poly(3-(trimethoxysilyl)propyl methacrylate) segment; quaternized groups NATIONAL SCIENCE FOUNDATION 2008-06-12 — — US claimed
WO-2008021500-A2 MODIFICATION OF SURFACES WITH POLYMERS UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2008-02-21 — — WO claimed
US-12448479-B2 Radiation curable and printable composition HENKEL AG & CO. KGAA (DE) 2025-10-21 — — US disclosed
US-12384099-B2 Dual cure epoxy formulations for 3D printing applications HENKEL AG & CO. KGAA (DE) 2025-08-12 — — US disclosed
US-12338346-B2 Radiation curable composition with improved mechanical properties HENKEL AG & CO. KGAA (DE) 2025-06-24 — — US disclosed
US-12296527-B2 Dual cure polyurethane formulations for 3D printing applications HENKEL AG & CO. KGAA (DE) 2025-05-13 — — US disclosed
CN-117157370-B Adhesive layer for flexographic printing plate mounting tape 3M创新有限公司 2025-03-18 — — CN disclosed
US-20240199919-A1 ADHESIVE LAYER FOR FLEXOGRAPHIC PLATE MOUNTING TAPE 3M INNOVATIVE PROPERTIES COMPANY 2024-06-20 — — US disclosed
EP-1302521-A2 Pressure sensitive polyacrylate adhesive Tesa AG (DE) 2003-04-16 — — EP disclosed
WO-2003000819-A1 STRIPPABLE SYSTEMS CONTAINING AT LEAST ONE ADHESIVE MASS BASED ON AT LEAST ONE BLOCK COPOLYMER HAVING THE UNIT P(A)-P(B)-P(A) TESA AG (DE) 2003-01-03 — — WO disclosed
US-6458864-B1 CHAIN TRANSFER GROUPS OF THE FORMULA ARE SUITABLE FOR THE THERMAL PREPARATION OF MACROPHOTOINITIATORS WHICH ARE POLYMERIZED PHOTOCHEMICALLY TO GIVE BLOCK-COPOLYMERS. CIBA SPECIALTY CHEMICALS CORPORATION 2002-10-01 — — US disclosed
EP-1177182-A1 NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS Ciba SC Holding AG (CH) 2002-02-06 — — EP disclosed
EP-1086145-A1 NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS Ciba SC Holding AG (CH) 2001-03-28 — — EP disclosed
WO-2000068218-A1 NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-11-16 — — WO disclosed
WO-1999062961-A1 NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-12-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130058910-A1 DECONTAMINATION OF CHEMICAL AND BIOLOGICAL AGENTS DDT, LPO, DDO CES1 243/4885SRC 164/4885CES2 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.