SCHEMBL11560426

SCHEMBL11560426

NOC(N=NC(O)(C(=O)c1ccccc1)c1ccccc1)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.41
SRC P12931 1/20 0.37
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
MAPK1 P28482 1/20 0.32
MAPT P10636 3/20 0.32
CYP2C19 P33261 2/20 0.32
POLB P06746 1/20 0.32
CYP3A4 P08684 1/20 0.32
PARP1 P09874 1/20 0.32
TSHR P16473 1/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
TNF P01375 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50344 0.84 CES1 (0.48) CES1SRCNPC1RAB9AMAPK1
SCHEMBL18669365 0.72 CES1 (0.47) CES1SRCMAPK1MAPTCYP2C19
SCHEMBL16280591 0.71 CES1 (0.50) CES1SRCMAPK1MAPTCYP2C19
SCHEMBL9941263 0.69 CES1 (0.38) CES1SRCMAPK1MAPTPOLB
SCHEMBL1476483 0.69 CES1 (0.56) CES1SRCMAPK1MAPTCYP2C19
SCHEMBL11431031 0.68 CES1 (0.43) CES1SRCMAPK1MAPTCYP2C19
SCHEMBL1079930 0.67 CES1 (0.54) CES1SRCMAPK1MAPTCYP2C19
SCHEMBL1395205 0.66 CES1 (0.53) CES1SRCMAPK1MAPTCYP2C19
SCHEMBL680607 0.65 CES1 (0.57) CES1SRCNPC1RAB9AMAPK1
Acetic Acid SCHEMBL4779742 0.65 CES1 (0.56) CES1SRCMAPTCYP2C19POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4169705-A Coloration process IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-10-02 US disclosed