Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50344 | 0.82 | CES1 (0.48) | CES1SRCPTPN1MAPTCYP3A4 | |
| SCHEMBL18669365 | 0.73 | CES1 (0.47) | CES1SRCPTPN1MAPTCYP3A4 | |
| SCHEMBL1252890 | 0.72 | CES1 (0.46) | CES1SRCMAPTCYP3A4MEN1 | |
| SCHEMBL1395461 | 0.72 | CES1 (0.50) | CES1SRCMAPTCYP3A4MEN1 | |
| SCHEMBL5483963 | 0.72 | CES1 (0.46) | CES1SRCPTPN1MAPTCYP3A4 | |
| SCHEMBL11431031 | 0.69 | CES1 (0.43) | CES1SRCPTPN1MAPTCYP3A4 | |
| SCHEMBL754131 | 0.69 | CES1 (0.47) | CES1SRCMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11560426 | 0.69 | CES1 (0.41) | CES1SRCMAPTCYP3A4KMT2A | |
| SCHEMBL1079930 | 0.68 | CES1 (0.54) | CES1SRCMAPTCYP3A4MEN1 | |
| SCHEMBL4769359 | 0.68 | KCNN4 (0.48) | CES1SRCMAPTCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651997-A1 | FOAMS OF HIGH THERMAL STABILITY | Bayer Intellectual Property GmbH (DE) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080185-A1 | FOAMS OF HIGH THERMAL STABILITY | BAYER MATERIALSCIENCE AG (DE) | 2012-06-21 | — | — | WO | disclosed |