Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12388 | 0.92 | — | — | |
| SCHEMBL29406334 | 0.92 | — | — | |
| SCHEMBL27823792 | 0.89 | TRPA1 (0.94) | TRPA1TDP1TP53ALOX15LMNA | |
| Ammonia Solution, Strong SCHEMBL27929342 | 0.89 | TRPA1 (0.94) | TRPA1TDP1TP53ALOX15LMNA | |
| SCHEMBL28075525 | 0.89 | TRPA1 (0.94) | TRPA1TDP1TP53ALOX15LMNA | |
| SCHEMBL27803153 | 0.89 | TRPA1 (0.94) | TRPA1TDP1TP53ALOX15LMNA | |
| SCHEMBL1937639 | 0.89 | TRPA1 (0.94) | TRPA1TDP1TP53ALOX15LMNA | |
| Methane SCHEMBL5950714 | 0.89 | TRPA1 (0.94) | TRPA1TDP1TP53ALOX15LMNA | |
| Phenol SCHEMBL6276525 | 0.88 | TRPA1 (0.73) | TRPA1TDP1TP53ALOX15LMNA | |
| Formaldehyde SCHEMBL27665137 | 0.84 | TRPA1 (0.84) | TRPA1TDP1TP53ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080124807-A1 | Protein tagging reagents | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080124807-A1 | Protein tagging reagents | TH, TPH1, TPH2 | TRPA1 4850/4885TDP1 1133/4885TP53 3082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.