Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1363307 | 0.89 | BCL2 (0.43) | BCL2IDO1CNR2 | |
| SCHEMBL5034607 | 0.88 | BCL2 (0.49) | BCL2PTGS2FGFR1DHFR | |
| SCHEMBL5080192 | 0.84 | KMO (0.45) | — | |
| SCHEMBL5547358 | 0.80 | BCL2 (0.62) | BCL2IDO1PTGS2FGFR1NISCH | |
| SCHEMBL29489424 | 0.80 | BCL2 (0.62) | BCL2IDO1PTGS2FGFR1NISCH | |
| SCHEMBL29100426 | 0.79 | BCL2 (0.41) | BCL2CNR2 | |
| SCHEMBL2135450 | 0.79 | KMO (0.55) | — | |
| SCHEMBL12894987 | 0.79 | BCL2 (0.78) | BCL2PTGS2DHFR | |
| SCHEMBL13818514 | 0.77 | BCL2 (0.71) | BCL2IDO1PTGS2FGFR1NISCH | |
| SCHEMBL172981 | 0.77 | BCL2 (0.61) | BCL2IDO1PTGS2DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402645-B2 | Soluble polyfunctional vinyl aromatic polymer and method of producing the same | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2008-07-22 | — | — | US | disclosed |
| US-20070155923-A1 | Soluble polyfunctional vinyl aromatic polymer and method of producing the same | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2007-07-05 | — | — | US | disclosed |