Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2135450 | 0.93 | KMO (0.55) | KMOPRSS1PRSS2PRSS3LMNA | |
| SCHEMBL29066701 | 0.91 | LMNA (0.45) | KMOPRSS1PRSS2PRSS3LMNA | |
| SCHEMBL167439 | 0.87 | FURIN (0.43) | LMNAHDAC8TDP1MAPTL3MBTL1 | |
| SCHEMBL4212859 | 0.86 | RXRA (0.61) | RXRARXRB | |
| SCHEMBL5034612 | 0.84 | BCL2 (0.54) | — | |
| SCHEMBL16155815 | 0.84 | MAPT (0.60) | KMOLMNAGAABRD4BRD2 | |
| SCHEMBL6252421 | 0.84 | FURIN (0.41) | LMNATDP1MAPTL3MBTL1 | |
| SCHEMBL17421702 | 0.84 | FURIN (0.41) | LMNATDP1MAPTL3MBTL1 | |
| SCHEMBL30834584 | 0.84 | FURIN (0.41) | LMNATDP1MAPTL3MBTL1 | |
| SCHEMBL5034607 | 0.83 | BCL2 (0.49) | LMNAGAATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402646-B2 | Polymerization of diisopropenylbenzene | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-22 | — | — | US | disclosed |
| US-20060270815-A1 | Polymerization of diisopropenylbenzene | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-11-30 | — | — | US | disclosed |