Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034768 | 0.84 | NPSR1 (0.44) | NPSR1TSHRMAPK1USP2KMT2A | |
| SCHEMBL5034770 | 0.84 | NPSR1 (0.43) | NPSR1TSHRMAPK1USP2KMT2A | |
| SCHEMBL12236721 | 0.73 | NPSR1 (0.53) | NPSR1TSHRMAPK1USP2KMT2A | |
| SCHEMBL2395888 | 0.71 | NPSR1 (0.49) | NPSR1TSHRMAPK1USP2KMT2A | |
| SCHEMBL13925444 | 0.66 | NPSR1 (1.00) | NPSR1TSHRMAPK1USP2KMT2A | |
| SCHEMBL5040550 | 0.65 | NPSR1 (0.48) | NPSR1TSHRMAPK1USP2KMT2A | |
| SCHEMBL448931 | 0.64 | NR3C1 (0.44) | — | |
| SCHEMBL13727140 | 0.64 | NPSR1 (0.80) | NPSR1TSHRMAPK1USP2KMT2A | |
| SCHEMBL2395836 | 0.64 | MKNK1 (0.43) | NPSR1TSHRMAPK1USP2LMNA | |
| SCHEMBL12236725 | 0.64 | LMNA (0.37) | NPSR1TSHRMAPK1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1944290-A1 | NOVEL 1-2-DIHYDROQUINOLINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2008-07-16 | — | — | EP | disclosed |