SCHEMBL5034772

SCHEMBL5034772

C1=NNOc2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.42
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2094585 1.00 TRPA1 (0.42) TRPA1ALOX5
SCHEMBL3194987 0.98 TRPA1 (0.41) TRPA1
SCHEMBL18867853 0.68 TRPA1 (0.38) TRPA1
SCHEMBL23727987 0.64
SCHEMBL452614 0.62
SCHEMBL3074957 0.62 ALOX5 (0.37) TRPA1ALOX5
SCHEMBL20499 0.60 TRPA1 (0.43) TRPA1
SCHEMBL1781023 0.60 TRPA1 (0.43) TRPA1
SCHEMBL3662203 0.60 MAPT (0.37) TRPA1ALOX5
SCHEMBL8924 0.60 MAPT (0.37) TRPA1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1911754-B1 Dipeptidyl peptidase inhibitors TAKEDA PHARMACEUTICAL (JP) 2013-10-09 EP claimed
EP-1911754-A1 Dipeptidyl peptidase inhibitors Takeda Pharmaceutical Company Limited (JP) 2008-04-16 EP claimed