Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29800306 | 0.77 | TRPA1 (0.41) | TRPA1 | |
| SCHEMBL244607 | 0.77 | TRPA1 (0.41) | TRPA1 | |
| Hydrochloric Acid SCHEMBL8480734 | 0.76 | TRPA1 (0.39) | TRPA1 | |
| SCHEMBL31083336 | 0.70 | TRPA1 (0.42) | TRPA1 | |
| SCHEMBL208530 | 0.67 | TRPA1 (0.39) | TRPA1 | |
| SCHEMBL207083 | 0.67 | TRPA1 (0.39) | TRPA1 | |
| SCHEMBL239587 | 0.67 | TRPA1 (0.34) | TRPA1 | |
| SCHEMBL9935517 | 0.66 | TRPA1 (0.47) | TRPA1 | |
| SCHEMBL2493361 | 0.66 | — | — | |
| SCHEMBL23573691 | 0.64 | TRPA1 (0.46) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021410-B1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER (US) | 2006-12-27 | — | — | EP | claimed |
| US-20030078261-A1 | Prostaglandin agonists | CAMERON KIMBERLY O (US) | 2003-04-24 | — | — | US | claimed |
| US-6432964-B1 | A THIENYLPYRIMIDINE COMPOUND | AGREVO UK LIMITED (GB) | 2002-08-13 | — | — | US | claimed |
| EP-0934290-B1 | AMINOTHIAZOLE DERIVATIVES, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2002-04-17 | — | — | EP | claimed |
| EP-0299694-B1 | Acrylate fungicides | AVENTIS CROPSCIENCE UK LTD (GB) | 2000-10-11 | — | — | EP | claimed |
| EP-1021410-A1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER INC. (US) | 2000-07-26 | — | — | EP | claimed |
| WO-1999019300-A1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER INC. (US) | 1999-04-22 | — | — | WO | claimed |
| CN-117986273-A | Benzoxazine morpholine compound and preparation method and application thereof | 中国医学科学院药物研究所 | 2024-05-07 | — | — | CN | disclosed |
| CN-117069650-A | Alkynyl compound, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2023-11-17 | — | — | CN | disclosed |
| CN-113214288-B | Benzo [1,3] oxazine-oxazolidinone compound and preparation method and application thereof | 中国医学科学院药物研究所 | 2023-11-03 | — | — | CN | disclosed |
| US-11739131-B2 | Growth differentiation factor 15 (GDF-15) polypeptides | AMGEN INC. (US) | 2023-08-29 | — | — | US | disclosed |
| US-20230174484-A1 | ANTAGONISTS OF GPR39 PROTEIN | UNIV OREGON HEALTH & SCIENCE (US) | 2023-06-08 | — | — | US | disclosed |
| WO-2023076219-A2 | ANTAGONISTS OF GPR39 PROTEIN | VASOCARDEA, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| EP-0517301-A1 | Propenoic acid derivatives | AgrEvo UK Limited (GB) | 1992-12-09 | — | — | EP | disclosed |
| US-5093364-A | 5-FLUOROANTHRANILIC FUNGICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-03-03 | — | — | US | disclosed |
| WO-1991017152-A1 | PREPARATION OF PROPENOIC ACID DERIVATIVES | SCHERING AGROCHEMICALS LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |
| WO-1991007385-A1 | PREPARATION OF PROPENOIC ACID DERIVATIVES | SCHERING AGROCHEMICALS LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |
| EP-0416746-A2 | Fungicides containing an alkoxycarbonylvinyl group or an alkyloxyimino group | AGREVO UK LIMITED (GB) | 1991-03-13 | — | — | EP | disclosed |
| EP-0360417-A2 | Derivatives of 4-fluoroanthranilic acid and their use as fungicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1990-03-28 | — | — | EP | disclosed |
| EP-0299694-A2 | Acrylate fungicides | AgrEvo UK Limited (GB) | 1989-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174484-A1 | ANTAGONISTS OF GPR39 PROTEIN | GPR39, GPR139, GPR119 | TRPA1 421/4885 |
| US-11739131-B2 | Growth differentiation factor 15 (GDF-15) polypeptides | IGFBP5, IGFBP2, IGFBP1 | TRPA1 4740/4885 |
| US-20030078261-A1 | Prostaglandin agonists | PTGER1, PTGER4, PTGIR | TRPA1 1761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.