SCHEMBL5035199

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14190166	0.93	CYP3A4 (0.37)	CYP3A4NPSR1TSHRKMT2AHTT
	SCHEMBL5039048	0.93	CYP3A4 (0.43)	CYP3A4NPSR1TSHRKMT2AHTT
	SCHEMBL5032515	0.91	CYP3A4 (0.41)	CYP3A4IRAK4NPSR1TSHRKMT2A
	SCHEMBL5034722	0.89	CYP3A4 (0.44)	CYP3A4NPSR1TSHRHTTSMN1; SMN2
	SCHEMBL5034751	0.89	CYP3A4 (0.47)	CYP3A4NPSR1KMT2AHTTMEN1
	SCHEMBL5041208	0.89	CYP3A4 (0.41)	CYP3A4IRAK4NPSR1TSHRHTT
	SCHEMBL5034876	0.88	CYP3A4 (0.43)	CYP3A4IRAK4NPSR1TSHRKMT2A
	SCHEMBL5032643	0.88	FLT1 (0.38)	CYP3A4TSHRKMT2AMEN1ALDH1A1
	SCHEMBL5032631	0.87	CYP3A4 (0.37)	CYP3A4IRAK4NPSR1TSHRKMT2A
	SCHEMBL14190180	0.87	CDK8 (0.44)	CYP3A4KMT2AMEN1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.