SCHEMBL5034722

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5032515	0.95	CYP3A4 (0.41)	CYP3A4TSHRALDH1A1MAPTL3MBTL1
	SCHEMBL5041208	0.94	CYP3A4 (0.41)	CYP3A4TSHRALDH1A1MAPTL3MBTL1
	SCHEMBL5032602	0.93	CYP3A4 (0.40)	CYP3A4TSHRALDH1A1MAPTL3MBTL1
	SCHEMBL5039048	0.93	CYP3A4 (0.43)	CYP3A4TSHRALDH1A1MAPTL3MBTL1
	SCHEMBL5032525	0.90	CRHR1 (0.39)	CYP3A4TSHRALDH1A1MAPTFLT1
	SCHEMBL5032622	0.90	FLT1 (0.40)	CYP3A4TSHRALDH1A1MAPTGABRB2
	SCHEMBL5032527	0.90	ALDH1A1 (0.46)	CYP3A4TSHRALDH1A1MAPTFLT1
	SCHEMBL5035199	0.89	CYP3A4 (0.39)	CYP3A4TSHRALDH1A1MAPTL3MBTL1
	SCHEMBL14190166	0.89	CYP3A4 (0.37)	CYP3A4TSHRALDH1A1MAPTFLT1
	SCHEMBL5035872	0.89	LMNA (0.48)	CYP3A4TSHRMAPTL3MBTL1GABRA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.