Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034411 | 0.87 | HRH2 (0.32) | DGAT1 | |
| SCHEMBL5033942 | 0.86 | NPC1 (0.36) | — | |
| SCHEMBL5035296 | 0.86 | HRH2 (0.33) | CYP2D6 | |
| SCHEMBL5034357 | 0.83 | IKBKB (0.32) | CYP2D6DGAT1GFER | |
| SCHEMBL4588828 | 0.81 | HRH2 (0.32) | — | |
| SCHEMBL5034346 | 0.77 | IKBKB (0.44) | CYP1A2CYP3A4CYP2D6CYP2C19GFER | |
| SCHEMBL5037990 | 0.76 | IRAK4 (0.32) | — | |
| SCHEMBL14031214 | 0.71 | KMT2A (0.35) | CYP1A2CYP3A4CYP2D6CYP2C19GFER | |
| SCHEMBL4590382 | 0.66 | IKBKB (0.61) | CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL4595720 | 0.62 | IKBKB (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269291-A1 | Chemical Compounds | GLAXOSMITHKLINE LLC | 2008-10-30 | — | — | US | disclosed |
| US-20080269291-A1 | Chemical Compounds | GLAXOSMITHKLINE LLC | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269291-A1 | Chemical Compounds | IDO2, IKBKG, NFKBIA | CYP1A2 185/4885CYP3A4 2011/4885CYP2D6 2188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.