Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 4/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14031214 | 0.88 | KMT2A (0.35) | IKBKBCHUKHRH2GFERHTR2A | |
| SCHEMBL4588828 | 0.84 | HRH2 (0.32) | HRH2 | |
| SCHEMBL5035303 | 0.83 | CYP1A2 (0.32) | GFERCYP2D6DGAT1 | |
| SCHEMBL5033942 | 0.81 | NPC1 (0.36) | PGR | |
| SCHEMBL5035296 | 0.81 | HRH2 (0.33) | HRH2HTR2AHTR2CHTR2BPGR | |
| SCHEMBL5034411 | 0.80 | HRH2 (0.32) | HRH2PGRDGAT1 | |
| SCHEMBL5037990 | 0.79 | IRAK4 (0.32) | — | |
| SCHEMBL5035290 | 0.74 | IKBKB (0.52) | IKBKBCHUKGFERPGRCYP2D6 | |
| SCHEMBL31215809 | 0.62 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL31215522 | 0.62 | DGAT1 (0.31) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269291-A1 | Chemical Compounds | GLAXOSMITHKLINE LLC | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269291-A1 | Chemical Compounds | IDO2, IKBKG, NFKBIA | IKBKB 8/4885CHUK 28/4885HRH2 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.