Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 3/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.30 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035296 | 0.93 | HRH2 (0.33) | HRH2PGRRETPFKFB1PFKFB3 | |
| SCHEMBL5034357 | 0.80 | IKBKB (0.32) | HRH2PGRDGAT1 | |
| SCHEMBL5037990 | 0.79 | IRAK4 (0.32) | — | |
| SCHEMBL4595720 | 0.75 | IKBKB (0.45) | DRD2SLC6A4 | |
| SCHEMBL14031214 | 0.68 | KMT2A (0.35) | HRH2PGR | |
| SCHEMBL4590044 | 0.67 | IKBKB (0.46) | PFKFB1PFKFB3 | |
| SCHEMBL4590194 | 0.67 | IKBKB (0.46) | DRD2SLC6A4 | |
| SCHEMBL4589503 | 0.62 | IKBKB (0.65) | — | |
| SCHEMBL31215522 | 0.62 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL31215809 | 0.62 | DGAT1 (0.31) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269291-A1 | Chemical Compounds | GLAXOSMITHKLINE LLC | 2008-10-30 | — | — | US | disclosed |
| US-20080269291-A1 | Chemical Compounds | GLAXOSMITHKLINE LLC | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269291-A1 | Chemical Compounds | IDO2, IKBKG, NFKBIA | HRH2 270/4885SCN9A 4209/4885PGR 3610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.