Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.55 |
| ▸ | NAAA | Q02083 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1523403 | 0.98 | MIF (0.57) | MIFNAAAMAOAMAPTRXFP1 | |
| SCHEMBL29152182 | 0.96 | NAAA (0.58) | MIFNAAAMAOAMAPTRXFP1 | |
| SCHEMBL21694457 | 0.96 | MIF (0.55) | MIFNAAAMAOAMAPTRXFP1 | |
| Hydrochloric Acid SCHEMBL28503124 | 0.96 | MIF (0.55) | MIFNAAAMAOAMAPTRXFP1 | |
| SCHEMBL10456657 | 0.96 | MIF (0.55) | MIFNAAAMAOAMAPTRXFP1 | |
| SCHEMBL3465495 | 0.91 | HTR3A (0.57) | MIFNAAAMAOAMAPTRXFP1 | |
| P-Xylene SCHEMBL28772421 | 0.88 | SCN5A (0.52) | MIFNAAAMAOAMAPTRXFP1 | |
| Toluene SCHEMBL27574812 | 0.88 | SCN5A (0.49) | MIFNAAAMAOAMAPTRXFP1 | |
| SCHEMBL944031 | 0.81 | HIF1A (0.52) | MIFMAOAMAPTHTR3AMAOB | |
| SCHEMBL9819738 | 0.79 | NAAA (0.64) | MIFNAAAMAOAMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12221524-B2 | Polymerization initiator, curable composition, dental material, and preparation kit for curable composition | MITSUI CHEMICALS, INC. (JP) | 2025-02-11 | — | — | US | disclosed |
| CN-118139614-A | Sterile liposome-containing compositions and articles | 脂肪球有限公司 | 2024-06-04 | — | — | CN | disclosed |
| EP-3835329-B1 | POLYMERIZATION INITIATOR, CURABLE COMPOSITION, DENTAL MATERIAL, AND PREPARATION KIT FOR CURABLE COMPOSITION | MITSUI CHEMICALS INC (JP) | 2024-05-01 | — | — | EP | disclosed |
| CN-112920092-B | Prodrugs of glutamine analogues | 约翰霍普金斯大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-111479574-B | Compounds for the treatment and prevention of extracellular histone mediated pathologies | 澳大利亚国立大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-117462563-A | Compounds for the treatment and prevention of extracellular histone mediated pathologies | 澳大利亚国立大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-117427084-A | Compounds for the treatment and prevention of extracellular histone mediated pathologies | 澳大利亚国立大学 | 2024-01-23 | — | — | CN | disclosed |
| CN-117280030-A | Agents, compositions and methods for treating hypoxia and ischemia related conditions | 梅兰德制药公司 | 2023-12-22 | — | — | CN | disclosed |
| US-20230323084-A1 | POLYMERIZATION INITIATOR, CURABLE COMPOSITION, DENTAL MATERIAL, AND PREPARATION KIT FOR CURABLE COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2023-10-12 | — | — | US | disclosed |
| CN-116507327-A | Chewable formulations | 礼蓝动物保健有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-114828897-A | Modulation of cell viability | 麦考瑞大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114716390-A | Compositions and methods for treating and/or preventing necrosis of cells or tissue | ELA制药有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-108135863-B | EGR1 targeting molecules for the treatment of inflammatory and hyperproliferative conditions | 特拉维夫医疗中心医学研究基础设施和保健服务基金会 | 2021-07-27 | — | — | CN | disclosed |
| EP-3835329-A1 | POLYMERIZATION INITIATOR, CURABLE COMPOSITION, DENTAL MATERIAL, AND PREPARATION KIT FOR CURABLE COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2021-06-16 | — | — | EP | disclosed |
| US-20210130580-A1 | POLYMERIZATION INITIATOR, CURABLE COMPOSITION, DENTAL MATERIAL, AND PREPARATION KIT FOR CURABLE COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2021-05-06 | — | — | US | disclosed |
| WO-2020031897-A1 | POLYMERIZATION INITIATOR, CURABLE COMPOSITION, DENTAL MATERIAL, AND PREPARATION KIT FOR CURABLE COMPOSITION | 三井化学株式会社 | 2020-02-13 | — | — | WO | disclosed |
| CN-107690429-A | composition for the treatment and/or prevention of cell or tissue necrosis, specifically targeting cathepsin C and/or CE L a1 and/or CE L A3A and/or enzymes structurally related thereto | ELA制药有限公司 | 2018-02-13 | — | — | CN | disclosed |
| CN-107085113-A | Gelsolin diagnoses and treated the purposes of inflammatory disease | 布赖汉姆妇女医院有限公司 | 2017-08-22 | — | — | CN | disclosed |
| EP-1981343-A2 | TREATMENT OF INFLAMMATORY DISORDERS WITH TRIAZOLE COMPOUNDS | Barrier Therapeutics, Inc. (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007084542-A2 | TREATMENT OF INFLAMMATORY DISORDERS WITH TRIAZOLE COMPOUNDS | BARRIER THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |