Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGD | P52209 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298893 | 0.79 | — | — | |
| SCHEMBL3168971 | 0.79 | — | — | |
| SCHEMBL3159259 | 0.79 | — | — | |
| SCHEMBL3164843 | 0.79 | — | — | |
| SCHEMBL3159244 | 0.79 | — | — | |
| SCHEMBL16600448 | 0.78 | PDE4A (0.50) | PGDLMNAALDH1A1PDE4AUSP2 | |
| SCHEMBL28209217 | 0.76 | LMNA (0.36) | LMNAALDH1A1PDE4ATHRB | |
| SCHEMBL17881926 | 0.76 | LMNA (0.36) | LMNAALDH1A1PDE4ATHRB | |
| SCHEMBL16897691 | 0.76 | LMNA (0.36) | LMNAALDH1A1PDE4ATHRB | |
| SCHEMBL18902607 | 0.75 | PGD (0.43) | PGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896040-A2 | PHOSPHORAMIDATE ALKYLATOR PRODRUGS | Threshold Pharmaceuticals, Inc. (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007002931-A2 | PHOSPHORAMIDATE ALKYLATOR PRODRUGS | THRESHOLD PHARMACEUTICALS, INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| CN-1835962-A | Compositions and methods for treatment of disease with acetylated disaccharides | UNIV CALIFORNIA (US) | 2006-09-20 | — | — | CN | disclosed |