Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | LHCGR | P22888 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5037184 | 1.00 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL4418754 | 0.87 | CACNA1F (0.51) | ALDH1A1SMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL10915430 | 0.78 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2APDE4D | |
| SCHEMBL14285233 | 0.78 | LHCGR (0.56) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL4906981 | 0.74 | LHCGR (0.56) | PDE4DPDE4APDE4BPDE4CLHCGR | |
| SCHEMBL4421035 | 0.72 | ACHE (0.49) | ALDH1A1SMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL4427518 | 0.71 | MYC (0.46) | ALDH1A1SMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL14308657 | 0.70 | LHCGR (0.52) | MEN1NPC1RAB9AKMT2APDE4D | |
| SCHEMBL6928354 | 0.70 | LHCGR (0.58) | MEN1NPC1RAB9AKMT2ALHCGR | |
| SCHEMBL4426414 | 0.70 | LHCGR (0.57) | ALDH1A1SMN1; SMN2MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1886999-A2 | Bicyclic heteroaromatic compound | N.V. Organon (NL) | 2008-02-13 | — | — | EP | disclosed |