Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14847366 | 0.85 | NPY5R (0.46) | KDM4ELMNACCR1CCR5CCR8 | |
| Benzene SCHEMBL27860148 | 0.78 | NPY5R (0.37) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL59230 | 0.77 | — | — | |
| SCHEMBL23641148 | 0.77 | MEN1 (0.36) | KDM4ELMNACCR1CCR5CCR8 | |
| Biphenyl SCHEMBL27847762 | 0.76 | NPY5R (0.44) | KDM4ELMNACCR1CCR5CCR8 | |
| Hydrochloric Acid SCHEMBL1492471 | 0.75 | KDM4E (0.32) | KDM4ELMNACCR1CCR5CCR8 | |
| Methane SCHEMBL29087179 | 0.75 | KDM4E (0.32) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL27622904 | 0.75 | KDM4E (0.32) | KDM4ELMNACCR1CCR5CCR8 | |
| Water SCHEMBL27271178 | 0.75 | KDM4E (0.32) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL1703342 | 0.72 | KDM4E (0.56) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4157827-A1 | IL-17A MODULATORS | SANOFI (FR) | 2023-04-05 | — | — | EP | disclosed |
| EP-3483147-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Innocrin Pharmaceuticals, Inc. (US) | 2019-05-15 | — | — | EP | disclosed |
| US-20180221364-A1 | METALLOENZYME INHIBITOR COMPOUNDS | INNOCRIN PHARMACEUTICALS, INC. | 2018-08-09 | — | — | US | disclosed |
| US-20180221364-A1 | METALLOENZYME INHIBITOR COMPOUNDS | INNOCRIN PHARMACEUTICALS, INC. | 2018-08-09 | — | — | US | disclosed |
| US-20170143694-A1 | METALLOENZYME INHIBITOR COMPOUNDS | INNOCRIN PHARMACEUTICALS, INC. | 2017-05-25 | — | — | US | disclosed |
| US-20170143694-A1 | METALLOENZYME INHIBITOR COMPOUNDS | INNOCRIN PHARMACEUTICALS, INC. | 2017-05-25 | — | — | US | disclosed |
| US-9266906-B2 | Copper(I) complexes for optoelectronic devices | CYNORA GMBH (DE) | 2016-02-23 | — | — | US | disclosed |
| US-9266906-B2 | Copper(I) complexes for optoelectronic devices | CYNORA GMBH (DE) | 2016-02-23 | — | — | US | disclosed |
| EP-2729477-B1 | COPPER(I) COMPLEXES FOR OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2016-01-20 | — | — | EP | disclosed |
| US-20140235006-A1 | COPPER(I) COMPLEXES FOR OPTOELECTRONIC DEVICES | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-08-21 | — | — | US | disclosed |
| US-20120025177-A1 | Phosphorescent light-emitting iridium complex containing pyridyltriazole ligand | SOLVAY SA (BE) | 2012-02-02 | — | — | US | disclosed |
| CN-102307886-A | Phosphorescent light-emitting iridium complex containing pyridyltriazole ligand | PUSAN NAT UNIV IND COOP FOUND | 2012-01-04 | — | — | CN | disclosed |
| EP-2393820-A1 | PHOSPHORESCENT LIGHT-EMITTING IRIDIUM COMPLEX CONTAINING PYRIDYLTRIAZOLE LIGAND | Solvay SA (BE) | 2011-12-14 | — | — | EP | disclosed |
| US-8062767-B2 | Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter | Cheng, Chien-Hong (TW) | 2011-11-22 | — | — | US | disclosed |
| US-8062767-B2 | Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter | Cheng, Chien-Hong (TW) | 2011-11-22 | — | — | US | disclosed |
| US-8062767-B2 | Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter | Cheng, Chien-Hong (TW) | 2011-11-22 | — | — | US | disclosed |
| WO-2010090362-A1 | PHOSPHORESCENT LIGHT-EMITTING IRIDIUM COMPLEX CONTAINING PYRIDYLTRIAZOLE LIGAND | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2010-08-12 | — | — | WO | disclosed |
| US-20080217606-A1 | Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter | Cheng, Chien-Hong (TW) | 2008-09-11 | — | — | US | disclosed |
| US-20080217606-A1 | Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter | Cheng, Chien-Hong (TW) | 2008-09-11 | — | — | US | disclosed |
| US-20080217606-A1 | Organic light emitting diode containing a Ir complex having a novel ligand as a phosphorescent emitter | Cheng, Chien-Hong (TW) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180221364-A1 | METALLOENZYME INHIBITOR COMPOUNDS | MMEL1, GPX1, MPO | KDM4E 3322/4885LMNA 4266/4885CCR1 4531/4885 |
| US-20170143694-A1 | METALLOENZYME INHIBITOR COMPOUNDS | MMEL1, GPX1, MPO | KDM4E 3322/4885LMNA 4266/4885CCR1 4531/4885 |
| US-20120025177-A1 | Phosphorescent light-emitting iridium complex containing pyridyltriazole ligand | PPIP5K2, HPRT1, PHPT1 | KDM4E 3651/4885LMNA 3730/4885CCR1 3890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.