Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8994779 | 0.97 | USP2 (0.32) | USP2TSHRALDH1A1LMNACYP1A2 | |
| SCHEMBL1696866 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL1696806 | 0.94 | — | — | |
| SCHEMBL18835265 | 0.92 | — | — | |
| SCHEMBL1141181 | 0.85 | — | — | |
| Cyclohexanol SCHEMBL465356 | 0.85 | TSHR (0.40) | TSHRCYP2C19 | |
| SCHEMBL595778 | 0.82 | CYP2C19 (0.37) | USP2TSHRALDH1A1CYP2C19 | |
| SCHEMBL7748710 | 0.80 | CPB2 (0.44) | TSHRLMNABLMCPB2 | |
| SCHEMBL22898252 | 0.77 | — | — | |
| SCHEMBL30962320 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4597911-A | REACTING AMINO ALCOHOL WITH AMMONIUM BISULFITE OR AMMONIUM SULFATE | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-07-01 | — | — | US | claimed |
| US-4496762-A | Process for the preparation of N-(2-(cyclo-hexen-1-yl)ethyl)-4-methoxybenzeneacetamide | EASTMAN KODAK COMPANY (US) | 1985-01-29 | — | — | US | claimed |
| CN-106928073-A | A kind of preparation method of desmethylvenlafaxine | 石家庄度恩医药科技有限公司 | 2017-07-07 | — | — | CN | disclosed |
| EP-1450796-B1 | BENZOTHIAZOLE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-04-09 | — | — | EP | disclosed |
| US-6969712-B2 | Benzimidazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-29 | — | — | US | disclosed |
| US-20040044056-A1 | Benzimidazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-1342717-A1 | BENZIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6596718-B1 | A compound of formula I has a good affinity to the A2A receptor and is useful for the treatment of diseases mediated by this receptor. | HOFFMANN-LA ROCHE INC. | 2003-07-22 | — | — | US | disclosed |
| US-4597911-A | REACTING AMINO ALCOHOL WITH AMMONIUM BISULFITE OR AMMONIUM SULFATE | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-07-01 | — | — | US | disclosed |
| US-4496762-A | Process for the preparation of N-(2-(cyclo-hexen-1-yl)ethyl)-4-methoxybenzeneacetamide | EASTMAN KODAK COMPANY (US) | 1985-01-29 | — | — | US | disclosed |
| US-4443593-A | Salvage of polycarbonate wastes by conversion to monomeric hydroxycarbamoyl phenols | THE DOW CHEMICAL COMPANY (US) | 1984-04-17 | — | — | US | disclosed |
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |
| US-4341789-A | ANTISECRETORY, ANTIAGGLOMERANTS, BRONCHODILATOR AND ANTIFERTILITY AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-07-27 | — | — | US | disclosed |
| EP-0001900-B1 | 9-THIA-12-AZAPROSTANOIC ACID DERIVATIVES AND COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1982-04-07 | — | — | EP | disclosed |
| US-4225609-A | Interphenylene 9-thia-11-oxo-12-aza-prostanoic acids | MERCK & CO., INC. (US) | 1980-09-30 | — | — | US | disclosed |
| US-4201864-A | CHEMICAL INTERMEDIATES, PROSTAGLANDINS | BEECHAM GROUP LIMITED (GB) | 1980-05-06 | — | — | US | disclosed |
| US-4177283-A | ANTISECRETORY, ANTICOAGULANT, BRONCHODILATOR | BEECHAM GROUP LIMITED (GB) | 1979-12-04 | — | — | US | disclosed |
| EP-0001900-A1 | 9-Thia-12-azaprostanoic acid derivatives and compositions containing them | MERCK & CO. INC. (US) | 1979-05-16 | — | — | EP | disclosed |
| US-4138407-A | ANTISECRETORY, BRONCHODILATOR, ANTICOAGULANT | BEECHAM GROUP LIMITED (GB) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044056-A1 | Benzimidazole derivatives | GPR119, OPRL1, INSR | USP2 4219/4885TSHR 239/4885ALDH1A1 1851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.