Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707166 | 0.93 | AKR1B1 (0.52) | CYP1A2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL24440105 | 0.90 | CYP1A2 (0.56) | CYP1A2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL11701595 | 0.89 | AKR1B1 (0.51) | CYP1A2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL11706524 | 0.88 | MAPT (0.51) | CYP1A2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL1115123 | 0.84 | CYP1A2 (0.56) | CYP1A2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL14710258 | 0.81 | AKR1B1 (0.61) | SRD5A1SRD5A2MAPTRAB9AMITF | |
| SCHEMBL27426495 | 0.80 | SRD5A2 (0.57) | CYP1A2MAPK1SMN1; SMN2SRD5A2FFAR4 | |
| SCHEMBL9145294 | 0.80 | SRD5A1 (0.45) | SRD5A1SRD5A2RAB9AMITFHSP90AA1 | |
| SCHEMBL27717299 | 0.79 | MAPT (0.46) | CYP1A2HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL8458964 | 0.78 | SRD5A1 (0.49) | MAPK1SMN1; SMN2SRD5A1SRD5A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435718-B2 | Upper layer-forming composition and photoresist patterning method | JSR CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20120028198-A1 | UPPER LAYER-FORMING COMPOSITION AND PHOTORESIST PATTERNING METHOD | JSR CORPORATION (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20100003615-A1 | UPPER LAYER-FORMING COMPOSITION AND PHOTORESIST PATTERNING METHOD | JSR CORPORATION (JP) | 2010-01-07 | — | — | US | disclosed |
| US-20080261923-A1 | Alkene Mimics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-10-23 | — | — | US | disclosed |
| US-20080261923-A1 | Alkene Mimics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-10-23 | — | — | US | disclosed |
| EP-1950610-A1 | COMPOSITION FOR FORMING UPPER FILM AND METHOD FOR FORMING PHOTORESIST PATTERN | JSR Corporation (JP) | 2008-07-30 | — | — | EP | disclosed |
| US-20070027067-A1 | Transition-state Inhibitors of Pin1, alpha-Ketoamide-containing peptidomimetics, and synthesis thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20070027067-A1 | Transition-state Inhibitors of Pin1, alpha-Ketoamide-containing peptidomimetics, and synthesis thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-5428065-A | Treating central nervous system disorders | LILLY INDUSTRIES LIMITED (GB) | 1995-06-27 | — | — | US | disclosed |
| EP-0645370-A1 | Substituted m-xylylene diamines for the treatment of diseases of the central nervous system | LILLY INDUSTRIES LIMITED (GB) | 1995-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027067-A1 | Transition-state Inhibitors of Pin1, alpha-Ketoamide-containing peptidomimetics, and synthesis thereof | PIN1, PREP, PIN4 | CYP1A2 3646/4885HDAC3 819/4885MAPK1 681/4885 |
| US-20080261923-A1 | Alkene Mimics | PHOSPHO1, PARN, CHAMP1 | CYP1A2 4480/4885HDAC3 625/4885MAPK1 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.