SCHEMBL503789

SCHEMBL503789

COc1cccc([C@@H](O)C(=O)O)c1

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.58
BLM P54132 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
TSHR P16473 1/20 0.54
LMNA P02545 3/20 0.53
MAPK1 P28482 1/20 0.53
AOC3 Q16853 2/20 0.51
MTNR1A P48039 3/20 0.51
MTNR1B P49286 3/20 0.51
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
PTGS1 P23219 1/20 0.50
CHRM2 P08172 1/20 0.49
CHRM1 P11229 1/20 0.49
CHRM3 P20309 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6400603 1.00 L3MBTL1 (0.58) L3MBTL1BLMNPSR1TSHRLMNA
SCHEMBL503788 1.00 L3MBTL1 (0.58) L3MBTL1BLMNPSR1TSHRLMNA
Mandelic Acid SCHEMBL2010439 0.86 L3MBTL1 (0.52) L3MBTL1LMNAMAPK1AOC3MTNR1A
SCHEMBL22625898 0.86 L3MBTL1 (0.58) L3MBTL1AOC3MTNR1AMTNR1BCES2
SCHEMBL6402645 0.84 PTGS1 (0.53) BLMNPSR1TSHRLMNAMAPK1
SCHEMBL5527572 0.84 L3MBTL1 (0.65) L3MBTL1AOC3MTNR1AMTNR1BCES2
SCHEMBL11081245 0.84 L3MBTL1 (0.56) L3MBTL1AOC3MTNR1AMTNR1BCES2
SCHEMBL6396089 0.84 PTGS1 (0.53) BLMNPSR1TSHRLMNAMAPK1
SCHEMBL6396086 0.84 PTGS1 (0.53) BLMNPSR1TSHRLMNAMAPK1
SCHEMBL2871628 0.84 L3MBTL1 (0.56) L3MBTL1AOC3MTNR1AMTNR1BCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109467502-B Method for splitting mandelic acid compound enantiomer 湖南科技大学 2021-07-30 CN claimed
EP-3141284-B1 METHOD OF STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE OREAL (FR) 2019-08-28 EP claimed
EP-2029237-B1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE ORÉAL L (FR) 2016-10-12 EP claimed
US-20160074296-A1 METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN a-HYDROXY ACID DERIVATIVE L'OREAL (FR) 2016-03-17 US claimed
US-20130139844-A1 METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN ¤-HYDROXY ACID DERIVATIVE L'OREAL S.A. (FR) 2013-06-06 US claimed
US-20100300471-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE L'OREAL S.A. (FR) 2010-12-02 US claimed
EP-3893834-B1 STRAIGHTENING PROCESS FOR KERATIN FIBERS OREAL (FR) 2026-04-29 EP disclosed
US-12324849-B2 Process for reshaping keratin fibers L'OREAL (FR) 2025-06-10 US disclosed
EP-3843696-B1 PROCESS AND COMPOSITION FOR COLORING KERATIN FIBERS OREAL (FR) 2025-04-09 EP disclosed
EP-3694475-B1 PROCESS FOR RESHAPING KERATIN FIBERS OREAL (FR) 2025-01-22 EP disclosed
US-20240269050-A1 ELECTROPORATION PROCESS FOR DELIVERING A COMPOSITION COMPRISING AT LEAST ONE HYDROXY ACID COMPOUND L'OREAL (FR) 2024-08-15 US disclosed
WO-2024122393-A1 COMPOSITION FOR IMPROVED STRAIGHTENING OF KERATIN FIBERS L'OREAL (FR) 2024-06-13 WO disclosed
WO-2023110815-A1 EMULSION WITH ALPHA-HYDROXY ACID, UV FILTER AND POLYMER L'OREAL (FR) 2023-06-22 WO disclosed
US-4218380-A OXIDATION OF THE A-HYDROXY-ARYLACETIC ACID BAYER AKTIENGESELLSCHAFT (DE) 1980-08-19 US disclosed
US-4202699-A Lithoplates of quaternary ammonium salt compositions VICKERS LIMITED (GB) 1980-05-13 US disclosed
US-4126468-A Radiation sensitive compositions of quaternary ammonium salt and carboxylic acid sensitizer VICKERS LIMITED (GB) 1978-11-21 US disclosed
US-4018759-A BACTERICIDES SMITHKLINE CORPORATION (US) 1977-04-19 US disclosed
US-3957768-A BACTERICIDES SMITHKLINE CORPORATION (US) 1976-05-18 US disclosed
US-3946005-A BACTERICIDES SMITHKLINE CORPORATION (US) 1976-03-23 US disclosed
US-3943129-A BACTERICIDE SMITHKLINE CORPORATION (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100300471-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE KRT18, KLK5, HOGA1 L3MBTL1 4874/4885BLM 4293/4885NPSR1 4620/4885
US-12324849-B2 Process for reshaping keratin fibers KRT18, CD44, COL14A1 L3MBTL1 4628/4885BLM 1284/4885NPSR1 4854/4885
US-20160074296-A1 METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN a-HYDROXY ACID DERIVATIVE KRT18, HOGA1, CYP27B1 L3MBTL1 4870/4885BLM 4667/4885NPSR1 4027/4885
US-20130139844-A1 METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN ¤-HYDROXY ACID DERIVATIVE KRT18, HOGA1, CYP27B1 L3MBTL1 4871/4885BLM 4467/4885NPSR1 4297/4885
US-20240269050-A1 ELECTROPORATION PROCESS FOR DELIVERING A COMPOSITION COMPRISING AT LEAST ONE HYDROXY ACID COMPOUND KRT18, CD44, EPCAM L3MBTL1 4880/4885BLM 4392/4885NPSR1 4131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.