Phyllanthin

Phyllanthin

SCHEMBL503799

COC[C@H](Cc1ccc(OC)c(OC)c1)[C@H](COC)Cc1ccc(OC)c(OC)c1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.57
CA2 P00918 1/20 0.57
ALOX15 P16050 2/20 0.53
ALOX12 P18054 2/20 0.53
CYP3A4 P08684 2/20 0.51
MMP1 P03956 1/20 0.51
ATM Q13315 2/20 0.50
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 2/20 0.49
PPARG P37231 1/20 0.49
PPARD Q03181 1/20 0.49
PPARA Q07869 1/20 0.49
STAT3 P40763 1/20 0.47
POLB P06746 2/20 0.47
CYP19A1 P11511 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
FOS P01100 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phyllanthin SCHEMBL29350279 1.00 LDHA (0.57) LDHACA2ALOX15ALOX12CYP3A4
SCHEMBL4249167 0.81 LDHA (0.57) LDHACA2ALOX15ALOX12CYP3A4
SCHEMBL4245548 0.81 LDHA (0.57) LDHACA2ALOX15ALOX12CYP3A4
SCHEMBL4250071 0.81 LDHA (0.57) LDHACA2ALOX15ALOX12CYP3A4
SCHEMBL11911905 0.81 CYP3A4 (0.75) LDHACA2ALOX15ALOX12CYP3A4
SCHEMBL4072201 0.81 CYP3A4 (0.75) LDHACA2ALOX15ALOX12CYP3A4
SCHEMBL31570913 0.81 CYP3A4 (0.53) CA2CYP3A4ATMALDH1A1
SCHEMBL30637362 0.81 CYP3A4 (0.53) CA2CYP3A4ATMALDH1A1
SCHEMBL7217113 0.80 LDHA (0.51) LDHACA2ALOX15ALOX12ATM
Terameprocol SCHEMBL194588 0.79 ALOX15 (0.77) LDHACA2ALOX15ALOX12CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 621 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075452-A Application of phyllanthin in preparation of medicines for treating or preventing colonitis 2026-05-26 CN claimed
CN-122047015-A Data-driven wind turbine blade three-dimensional aerodynamic effect modeling method 西北工业大学 2026-05-15 CN claimed
CN-122014520-A Wind turbine aerodynamic performance prediction method and related device 中山大学 2026-05-12 CN claimed
CN-120120199-A BEM-based wind power main shaft bearing load spectrum prediction method and system 佛山大学 2025-06-10 CN claimed
CN-120068477-A Numerical simulation method and device for contra-rotating rotor considering nacelle coupling 西北工业大学 2025-05-30 CN claimed
CN-120046533-A Method, device, equipment, storage medium and program product for predicting load of fan blade 中材科技风电叶片股份有限公司 2025-05-27 CN claimed
CN-120030947-A Floating type fan floating body structure fatigue damage analysis method and system 中国海洋大学 2025-05-23 CN claimed
CN-120012626-A Wind turbine generator set visual modeling method considering pneumatic parameters and mechanical characteristics 国网辽宁省电力有限公司电力科学研究院 2025-05-16 CN claimed
CN-120012320-A Wind turbine blade hoisting transverse swing pneumatic damping identification method, system and risk prompting method 广东工业大学 2025-05-16 CN claimed
CN-120012270-A Iterative algorithm and equipment for evaluating aerodynamic performance of coaxial rotor wing of eVTOL aircraft 中国航空工业集团公司哈尔滨空气动力研究所 2025-05-16 CN claimed
CN-112084594-A Improved tidal current energy water turbine performance prediction method 河海大学 2020-12-15 CN claimed
CN-111798478-A Method for measuring icing thickness of front edge of blade of wind driven generator 重庆大学 2020-10-20 CN claimed
CN-107609243-B Design method of propeller blade 西北工业大学 2020-07-03 CN claimed
CN-111310382-A Variable speed fan blade design attack angle optimization method considering multiple operating conditions 南京理工大学 2020-06-19 CN claimed
US-20180280343-A1 TOPICAL SILIBININ FORMULATIONS AND USES THEREFOR NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2018-10-04 US claimed
CN-103585120-A Phyllanthus ruinaria dispersible tablet for treatment of liver disease, and preparation method thereof GUANGDONG GRAND PHARMACEUTICAL CO LTD 2014-02-19 CN claimed
US-7446243-B2 High herb, phyllanthin and hypophyllanthin yielding cultivar of Phyllanthus amarus ‘CIM-Jeevan’ COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2008-11-04 US claimed
CN-101028329-A Preparation method and application of phyllanthus urinaria dispersible tablet preparation XINGHAOJIAYU MEDICAL SCIENCE & (CN) 2007-09-05 CN claimed
US-20070166255-A1 Treatment of Topical Discomforts Including Acne, Sunburn, Diaper Rash, Wound, Wrinkles and Dandruff/Hair Loss by Natural Lignans via Fatty Acid Desaturase Inhibition GUPTA SHYAM K 2007-07-19 US claimed
US-20050050593-A1 High herb, phyllanthin and hypophyllanthin yielding cultivar of Phyllanthus amarus 'CIM-Jeevan' COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2005-03-03 US claimed