Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GALR1 | P47211 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | USP14 | P54578 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503816 | 0.81 | KDM4E (0.44) | EGLN1KDM4EUSP14CTSLCTSS | |
| SCHEMBL503508 | 0.71 | MEN1 (0.41) | MEN1KMT2AKDM4EUSP14MAPT | |
| SCHEMBL335074 | 0.70 | TP53 (0.44) | MEN1KMT2AKDM4ETP53MAPT | |
| SCHEMBL504146 | 0.70 | USP14 (0.41) | MEN1KMT2AKDM4EUSP14MAPT | |
| SCHEMBL504228 | 0.69 | EPHX2 (0.39) | GALR1EGLN1KDM4EUSP14ALDH1A1 | |
| SCHEMBL10051928 | 0.69 | KDM4E (0.57) | MEN1KMT2AKDM4EUSP14TP53 | |
| SCHEMBL334049 | 0.68 | TP53 (0.42) | MEN1KMT2AKDM4ETP53MAPT | |
| SCHEMBL10051929 | 0.68 | USP14 (0.39) | MEN1KMT2AKDM4EUSP14 | |
| SCHEMBL333231 | 0.68 | MEN1 (0.48) | MEN1KMT2AKDM4EUSP14TP53 | |
| SCHEMBL504103 | 0.68 | EPHX2 (0.41) | MEN1KMT2AKDM4EUSP14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120029016-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SW) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029016-A1 | Indoles Useful in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | MEN1 2934/4885KMT2A 1783/4885GALR1 398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.