SCHEMBL503853

SCHEMBL503853

CC1(C)CC(C)(c2ccccc2)c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
ADRB2 P07550 1/20 0.46
TP53 P04637 5/20 0.43
MAPT P10636 3/20 0.43
PLIN1 O60240 1/20 0.43
ALDH1A1 P00352 1/20 0.43
PLIN5 Q00G26 1/20 0.43
ABHD5 Q8WTS1 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
SIGMAR1 Q99720 1/20 0.41
ATM Q13315 1/20 0.39
USP2 O75604 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
FSHR P23945 1/20 0.37
LMNA P02545 2/20 0.37
HTT P42858 1/20 0.37
MAPK1 P28482 1/20 0.36
OPRM1 P35372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29436894 1.00 MEN1 (0.46) MEN1KMT2ANPSR1ADRB2TP53
Water SCHEMBL27831248 0.98 MEN1 (0.45) MEN1KMT2ANPSR1ADRB2TP53
Fluorobenzene SCHEMBL17956587 0.91 MEN1 (0.41) MEN1KMT2ANPSR1ADRB2TP53
SCHEMBL23795268 0.89 MEN1 (0.50) MEN1KMT2ANPSR1ADRB2TP53
SCHEMBL17956590 0.86 TP53 (0.39) MEN1KMT2ANPSR1ADRB2TP53
SCHEMBL8948017 0.86 OPRM1 (0.40) MEN1KMT2ANPSR1ADRB2TP53
SCHEMBL10910475 0.85 MEN1 (0.43) MEN1KMT2ANPSR1ADRB2TP53
SCHEMBL28524816 0.84 ATM (0.39) MEN1KMT2ANPSR1ADRB2TP53
SCHEMBL10711448 0.84 TP53 (0.41) MEN1KMT2ANPSR1ADRB2TP53
SCHEMBL807632 0.84 MEN1 (0.44) MEN1KMT2ANPSR1ADRB2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 575 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115011043-A Ethylene propylene rubber insulating composition and preparation method thereof 东南大学 2022-09-06 CN claimed
CN-114436848-A Synthesis method of 5(6) -amino-1- (4-aminophenyl) -1,3,3-trimethylindane 山东华夏神舟新材料有限公司 2022-05-06 CN claimed
CN-113122052-A Ink composition TCL集团股份有限公司 2021-07-16 CN claimed
EP-2859069-B1 METHOD AND APPARATUS FOR TREATING PETROLEUM EQUIPMENT FERRARA MARCELLO (IT) 2020-10-14 EP claimed
CN-106883093-B Synthesis method of high-purity bromotrimethylphenyl hydrindene 山东润科化工股份有限公司 2020-05-08 CN claimed
US-20200075862-A1 INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2020-03-05 US claimed
CN-106748963-B Polyamide-imides and preparation method thereof containing indane structural 北京航空航天大学 2019-08-02 CN claimed
CN-108865300-A A kind of fuel system multiple-effect non-dismounting cleaning agent 深圳市龙威科技发展有限公司 2018-11-23 CN claimed
EP-3401305-A1 INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2018-11-14 EP claimed
EP-3051618-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME MITSUBISHI CHEM CORP (JP) 2018-11-14 EP claimed
EP-0076471-B1 STABILISATION OF POLYETHER OR POLYESTER MOULDING COMPOUNDS AGAINST PREMATURE REACTION HOECHST AKTIENGESELLSCHAFT (DE) 1985-12-18 EP claimed
US-4463189-A ADDING 2,4-DIPHENYL-4-METHYL-2-PENTENE AND 2,4-DIPHENYL-4-METHYL-1-PENTENE HOECHST AKTIENGESELLSCHAFT (DE) 1984-07-31 US claimed
EP-0076471-A2 Stabilisation of polyether or polyester moulding compounds against premature reaction HOECHST AKTIENGESELLSCHAFT (DE) 1983-04-13 EP claimed
US-4337319-A CONTAINING ORGANIC BROMINE COMPOUND AND A SYNERGIST CHEMISCHE WERKE HULS AG (DE) 1982-06-29 US claimed
EP-0014764-B1 FINELY DIVIDED, EXPANDABLE, SELF EXTINGUISHING STYRENE POLYMERS CHEMISCHE WERKE HÜLS AG (DE) 1981-11-11 EP claimed
EP-0014765-B1 PROCESS FOR THE PREPARATION OF 1-PHENYL-1,3,3-TRIMETHYLINDANE CHEMISCHE WERKE HÜLS AG (DE) 1981-09-23 EP claimed
EP-0014770-B1 PROCESS FOR WORKING UP THE CUMENE RECOVERED FROM THE HOCK-SYNTHESIS OF PHENOL CHEMISCHE WERKE HÜLS AG (DE) 1981-09-02 EP claimed
US-4286071-A MOLDING MATERIALS CONTAINING A BROMINE-CONTAINING COMPOUND AND A SYNERGISTIC AROMATIC HYDROCARBON; FIREPROOFING CHEMISCHE WERKE HULS AG (DE) 1981-08-25 US claimed
EP-0014765-A1 Process for the preparation of 1-phenyl-1,3,3-trimethylindane CHEMISCHE WERKE HÜLS AG (DE) 1980-09-03 EP claimed
US-3939095-A PHENYLINDANES, ADDITION COPOLYMERS BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-02-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200075862-A1 INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS KCNJ2, KCNA2, CYP2J2 MEN1 2274/4885KMT2A 1499/4885NPSR1 1142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.