Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.88 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038649 | 1.00 | ADRB2 (0.88) | ADRB2ADRB3CHRM3 | |
| SCHEMBL4990175 | 0.94 | ADRB2 (1.00) | ADRB2CHRM3 | |
| SCHEMBL5034331 | 0.94 | ADRB2 (1.00) | ADRB2CHRM3 | |
| SCHEMBL5034267 | 0.91 | ADRB2 (0.74) | ADRB2ADRB3CHRM3 | |
| SCHEMBL5034266 | 0.91 | ADRB2 (0.74) | ADRB2ADRB3CHRM3 | |
| SCHEMBL5042222 | 0.87 | ADRB2 (0.68) | ADRB2ADRB3CHRM3 | |
| SCHEMBL5042226 | 0.87 | ADRB2 (0.68) | ADRB2ADRB3CHRM3 | |
| SCHEMBL2455524 | 0.86 | ADRB2 (1.00) | ADRB2ADRB3CHRM3 | |
| SCHEMBL2455522 | 0.86 | ADRB2 (1.00) | ADRB2ADRB3CHRM3 | |
| SCHEMBL5037141 | 0.86 | ADRB2 (0.70) | ADRB2ADRB3CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351742-B2 | Sulfonamide derivatives for the treatment of diseases | PFIZER INC. (US) | 2008-04-01 | — | — | US | claimed |
| EP-1708992-B1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES | PFIZER LTD (GB) | 2007-08-08 | — | — | EP | claimed |
| US-20050171147-A1 | Sulfonamide derivatives for the treatment of diseases | PFIZER INC. | 2005-08-04 | — | — | US | claimed |
| US-7351742-B2 | Sulfonamide derivatives for the treatment of diseases | PFIZER INC. (US) | 2008-04-01 | — | — | US | disclosed |
| EP-1708992-B1 | SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES | PFIZER LTD (GB) | 2007-08-08 | — | — | EP | disclosed |
| US-20050171147-A1 | Sulfonamide derivatives for the treatment of diseases | PFIZER INC. | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171147-A1 | Sulfonamide derivatives for the treatment of diseases | SULT2A1, STS, SULT1A1 | ADRB2 2148/4885ADRB3 2520/4885CHRM3 1774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.