Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14367747 | 0.89 | PAOX (0.38) | CA1CA2NOD1 | |
| SCHEMBL2704033 | 0.89 | AKR1B1 (0.39) | MEN1KMT2ATSHR | |
| SCHEMBL10521386 | 0.89 | AKR1B1 (0.39) | MEN1KMT2ATSHR | |
| SCHEMBL2704035 | 0.89 | AKR1B1 (0.39) | MEN1KMT2ATSHR | |
| SCHEMBL563000 | 0.85 | TSHR (0.47) | CA2KDM4ETSHR | |
| SCHEMBL4941280 | 0.85 | TSHR (0.47) | CA2KDM4ETSHR | |
| SCHEMBL562999 | 0.85 | TSHR (0.47) | CA2KDM4ETSHR | |
| SCHEMBL7342396 | 0.84 | CA1 (0.44) | CA1CA2NOD1 | |
| SCHEMBL14367745 | 0.84 | CA1 (0.44) | CA1CA2NOD1 | |
| SCHEMBL5042185 | 0.84 | ALDH1A1 (0.46) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339669-B1 | N-ALKYLATED GABA COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB PHARMA SA (BE) | 2008-06-04 | — | — | EP | claimed |
| US-7112612-B2 | N-alkylated GABA compounds, processes for their preparation and their use as medicaments | UCB S.A. (BE) | 2006-09-26 | — | — | US | claimed |
| US-20040058991-A1 | N-alkylated gaba compounds, processes for their preparation and their use as medicaments | UCB S.A. (BE) | 2004-03-25 | — | — | US | claimed |
| EP-1339669-B1 | N-ALKYLATED GABA COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB PHARMA SA (BE) | 2008-06-04 | — | — | EP | disclosed |
| US-7112612-B2 | N-alkylated GABA compounds, processes for their preparation and their use as medicaments | UCB S.A. (BE) | 2006-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058991-A1 | N-alkylated gaba compounds, processes for their preparation and their use as medicaments | GABBR1, GABRB1, GABRB2 | CA1 1020/4885CA2 941/4885SOAT1 2160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.