Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5049002 | 0.81 | LTA4H (0.43) | NPC1RAB9AHPGDTP53 | |
| SCHEMBL5044417 | 0.80 | FFAR1 (0.47) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL5046558 | 0.80 | FFAR1 (0.47) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL5047701 | 0.80 | FFAR1 (0.47) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL5048982 | 0.77 | FFAR1 (0.44) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL6783491 | 0.75 | FFAR1 (0.44) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL1851716 | 0.74 | FFAR1 (0.44) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL1853472 | 0.74 | FFAR1 (0.44) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL1854091 | 0.74 | FFAR1 (0.44) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL1849960 | 0.74 | FFAR1 (0.44) | FFAR1FFAR4MMP2MMP12KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |