Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5039769 | 0.77 | FFAR1 (0.46) | FFAR1FFAR4CYP3A4TSHRMMP2 | |
| SCHEMBL6783491 | 0.77 | FFAR1 (0.44) | FFAR1FFAR4CYP3A4TSHRMMP2 | |
| SCHEMBL1855384 | 0.76 | ACHE (0.43) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL1853472 | 0.76 | FFAR1 (0.44) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL1851716 | 0.76 | FFAR1 (0.44) | FFAR1FFAR4MMP2MMP12KCNH2 | |
| SCHEMBL1855383 | 0.74 | FFAR1 (0.42) | FFAR1FFAR4CYP3A4TSHRMMP2 | |
| SCHEMBL1852067 | 0.72 | FFAR1 (0.49) | FFAR1FFAR4CYP3A4TSHRMMP2 | |
| SCHEMBL1850760 | 0.72 | FFAR1 (0.49) | FFAR1FFAR4CYP3A4TSHRMMP2 | |
| SCHEMBL1859814 | 0.72 | FFAR1 (0.49) | FFAR1FFAR4CYP3A4TSHRMMP2 | |
| SCHEMBL5886652 | 0.71 | FFAR1 (0.63) | FFAR1FFAR4MMP2MMP12KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |