Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048821 | 1.00 | NAAA (0.61) | NAAAL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL6023358 | 0.87 | MLYCD (0.54) | NAAAL3MBTL1HDAC3HDAC1SMN1; SMN2 | |
| SCHEMBL6721904 | 0.87 | MLYCD (0.54) | NAAAL3MBTL1HDAC3HDAC1SMN1; SMN2 | |
| SCHEMBL6718534 | 0.84 | NAAA (0.73) | NAAAL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL5045053 | 0.84 | NAAA (0.52) | NAAAL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL27601086 | 0.80 | NAAA (0.63) | NAAAL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL5039785 | 0.80 | NAAA (0.63) | NAAAL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL5048823 | 0.80 | NAAA (0.63) | NAAAL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL5045561 | 0.78 | NAAA (0.60) | NAAAL3MBTL1HDAC3HDAC1HDAC2 | |
| SCHEMBL1854271 | 0.78 | NAAA (0.56) | NAAAL3MBTL1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |