Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023358 | 1.00 | MLYCD (0.54) | MLYCDL3MBTL1NAAAMEN1ALDH1A1 | |
| SCHEMBL5048821 | 0.87 | NAAA (0.61) | MLYCDL3MBTL1NAAAALDH1A1SMN1; SMN2 | |
| SCHEMBL5039780 | 0.87 | NAAA (0.61) | MLYCDL3MBTL1NAAAALDH1A1SMN1; SMN2 | |
| SCHEMBL28929298 | 0.82 | MLYCD (0.76) | MLYCDL3MBTL1NAAAMEN1ALDH1A1 | |
| SCHEMBL5039922 | 0.82 | MLYCD (0.58) | MLYCDL3MBTL1NAAAMEN1ALDH1A1 | |
| SCHEMBL6022530 | 0.82 | MLYCD (0.58) | MLYCDL3MBTL1NAAAMEN1ALDH1A1 | |
| SCHEMBL1858482 | 0.82 | MLYCD (0.55) | MLYCDL3MBTL1NAAAMEN1ALDH1A1 | |
| SCHEMBL1852144 | 0.82 | MLYCD (0.55) | MLYCDL3MBTL1NAAAMEN1ALDH1A1 | |
| SCHEMBL13577932 | 0.81 | MLYCD (0.73) | MLYCDL3MBTL1NAAAMEN1ALDH1A1 | |
| SCHEMBL5039932 | 0.81 | MLYCD (0.62) | MLYCDL3MBTL1NAAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | claimed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | claimed |