SCHEMBL5032141

SCHEMBL5032141

C=C(C)C(=O)OCCOc1[c]cccc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.42
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 5/20 0.38
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
ELANE P08246 1/20 0.34
ALDH1A1 P00352 4/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
LMNA P02545 3/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.32
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
TP53 P04637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9324825 0.84 ALDH1A1 (0.41) THRBHTTTDP1TSHRALDH1A1
SCHEMBL33450 0.81 THRB (0.44) THRBPOLBAPEX1HTTTDP1
SCHEMBL15303251 0.78 THRB (0.47) THRBPOLBAPEX1HTTTDP1
SCHEMBL4950927 0.78 TDP1 (0.47) THRBPOLBAPEX1HTTTDP1
SCHEMBL2237469 0.78 ELANE (0.46) TDP1TSHRELANEALDH1A1KDM4E
SCHEMBL10580556 0.78 THRB (0.50) THRBPOLBAPEX1HTTTDP1
SCHEMBL27773558 0.77 TDP1 (0.49) THRBPOLBAPEX1HTTTDP1
Methacrylic Acid SCHEMBL17911799 0.77 TDP1 (0.58) THRBPOLBAPEX1HTTTDP1
SCHEMBL28824339 0.77 GPR174 (0.33) POLBELANEALDH1A1SMN1; SMN2KDM4E
SCHEMBL6238419 0.77 JAK2 (0.33) HTTTDP1ALDH1A1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1928941-A1 RESIN COMPOSITION FOR FORMING ULTRAVIOLET ABSORBING LAYER AND LAMINATE COMPRISING ULTRAVIOLET ABSORBING LAYER Nippon Shokubai Co.,Ltd. (JP) 2008-06-11 EP disclosed
WO-2007037501-A1 RESIN COMPOSITION FOR FORMING ULTRAVIOLET ABSORBING LAYER AND LAMINATE COMPRISING ULTRAVIOLET ABSORBING LAYER NIPPON SHOKUBAI CO., LTD. (JP) 2007-04-05 WO disclosed