Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744290 | 0.84 | PLA2G2A (0.46) | GPR84MTNR1AMTNR1BPTGS2MAOA | |
| SCHEMBL21611345 | 0.84 | PLA2G2A (0.46) | GPR84MTNR1AMTNR1BPTGS2MAOA | |
| SCHEMBL21611346 | 0.84 | PLA2G2A (0.46) | GPR84MTNR1AMTNR1BPTGS2MAOA | |
| SCHEMBL20746927 | 0.82 | CNR2 (0.47) | ALDH1A1DNM1 | |
| SCHEMBL10787032 | 0.82 | CNR2 (0.47) | ALDH1A1DNM1 | |
| SCHEMBL14447064 | 0.82 | CNR2 (0.47) | ALDH1A1DNM1 | |
| SCHEMBL10786365 | 0.82 | CNR2 (0.47) | ALDH1A1DNM1 | |
| SCHEMBL5044195 | 0.81 | GPR84 (0.38) | GPR84PTGS2 | |
| SCHEMBL13261439 | 0.80 | MAPT (0.47) | ALDH1A1 | |
| SCHEMBL24495927 | 0.77 | PLA2G2A (0.58) | MAOAMAOBPLA2G2ABLMAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1545502-A4 | KETO CANNABINOIDS WITH THERAPEUTIC INDICATIONS | UNIV CONNECTICUT (US) | 2008-12-24 | — | — | EP | disclosed |
| US-20070155701-A1 | KETO CANNABINOIDS WITH THERAPEUTIC INDICATIONS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2007-07-05 | — | — | US | disclosed |
| US-7183313-B2 | Keto cannabinoids with therapeutic indications | UNIVERSITY OF CONNECTICUT (US) | 2007-02-27 | — | — | US | disclosed |
| CN-1678303-A | Keto cannabinoids with therapeutic effect | UNIV CONNECTICUT (US) | 2005-10-05 | — | — | CN | disclosed |
| EP-1545502-A2 | KETO CANNABINOIDS WITH THERAPEUTIC INDICATIONS | THE UNIVERSITY OF CONNECTICUT (US) | 2005-06-29 | — | — | EP | disclosed |
| US-20050074408-A1 | Keto cannabinoids with therapeutic indications | UNIVERSITY OF CONNECTICUT (US) | 2005-04-07 | — | — | US | disclosed |
| WO-2004017922-A2 | KETO CANNABINOIDS WITH THERAPEUTIC INDICATIONS | UNIVERSITY OF CONNECTICUT (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050074408-A1 | Keto cannabinoids with therapeutic indications | CNR2, CNR1, FAAH | GPR84 421/4885MTNR1A 866/4885MTNR1B 542/4885 |
| US-20070155701-A1 | KETO CANNABINOIDS WITH THERAPEUTIC INDICATIONS | CNR2, CNR1, FAAH | GPR84 421/4885MTNR1A 866/4885MTNR1B 542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.