Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192623 | 0.85 | KMT2A (0.68) | KMT2AMAPTRAB9AALDH1A1CA1 | |
| SCHEMBL2703394 | 0.84 | LMNA (0.62) | KMT2AMAPTRAB9AALDH1A1CA1 | |
| SCHEMBL2700947 | 0.84 | RAB9A (0.62) | KMT2AMAPTRAB9AALDH1A1CA1 | |
| SCHEMBL10247032 | 0.83 | KCNK3 (0.45) | KMT2AMAPTALDH1A1CA1CA2 | |
| SCHEMBL2700957 | 0.83 | KMT2A (0.55) | KMT2AMAPTRAB9AALDH1A1CA1 | |
| SCHEMBL6819232 | 0.83 | CA1 (0.57) | KMT2AMAPTRAB9AALDH1A1CA1 | |
| SCHEMBL2699617 | 0.83 | POLB (0.55) | KMT2AMAPTRAB9AALDH1A1CA1 | |
| SCHEMBL27901571 | 0.82 | KMT2A (0.71) | KMT2AMAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL2698562 | 0.81 | ALDH1A1 (0.63) | KMT2AMAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL16190177 | 0.81 | CA1 (0.60) | KMT2AMAPTRAB9AALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058378-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF SALICYLANILIDES FOR TREATMENT OF HEPATITIS VIRUSES | ROMARK LABORATORIES L.C. (US) | 2012-05-03 | — | — | WO | disclosed |