Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5656608 | 0.82 | MMP1 (0.44) | MMP1MMP9MMP12ALDH1A1NPC1 | |
| SCHEMBL8633653 | 0.79 | MMP1 (0.42) | MMP1MMP9MMP12ALDH1A1NPC1 | |
| SCHEMBL15670569 | 0.79 | MMP1 (0.42) | MMP1MMP9MMP12ALDH1A1TSHR | |
| SCHEMBL4223881 | 0.78 | MMP1 (0.41) | MMP1MMP9MMP12ALDH1A1TSHR | |
| SCHEMBL29128596 | 0.78 | MMP1 (0.41) | MMP1MMP9MMP12ALDH1A1TSHR | |
| SCHEMBL15671059 | 0.78 | MMP1 (0.41) | MMP1MMP9MMP12ALDH1A1NPC1 | |
| SCHEMBL28403676 | 0.77 | MMP1 (0.40) | MMP1MMP9MMP12ALDH1A1TSHR | |
| SCHEMBL15670432 | 0.76 | MMP1 (0.42) | MMP1MMP9MMP12ALDH1A1TSHR | |
| SCHEMBL3246728 | 0.76 | MMP1 (0.47) | MMP1MMP9MMP12ALDH1A1NPC1 | |
| SCHEMBL1884481 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863376-B2 | Thermally controlled particulate core migration within polymer matrix | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2011-01-04 | — | — | US | disclosed |
| US-20080226995-A1 | Having thermodynamically reversible Diels Alder bond; noncoated; tissue engineering, permeable membranes, packaging materials | ARMY, UNITED STATES OF AMEICAS AS RESPRESENTED BY THE SECRETARY OF THE | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080226995-A1 | Having thermodynamically reversible Diels Alder bond; noncoated; tissue engineering, permeable membranes, packaging materials | EPCAM, DBNL, DSG1 | MMP1 821/4885MMP9 913/4885MMP12 2371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.