Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL538907 | 0.91 | ALDH1A1 (0.40) | MMP1MMP9MMP12ALDH1A1KMT2A | |
| SCHEMBL8633653 | 0.87 | MMP1 (0.42) | MMP1MMP9MMP12ALDH1A1KMT2A | |
| SCHEMBL4223881 | 0.83 | MMP1 (0.41) | MMP1MMP9MMP12ALDH1A1KMT2A | |
| SCHEMBL5656608 | 0.77 | MMP1 (0.44) | MMP1MMP9MMP12ALDH1A1KMT2A | |
| SCHEMBL5041398 | 0.77 | MMP1 (0.44) | MMP1MMP9MMP12ALDH1A1KMT2A | |
| SCHEMBL15670665 | 0.76 | ALDH1A1 (0.41) | MMP1MMP9MMP12ALDH1A1KMT2A | |
| SCHEMBL10708795 | 0.75 | MMP1 (0.40) | MMP1MMP9MMP12ALDH1A1KMT2A | |
| SCHEMBL15548622 | 0.75 | TSHR (0.50) | ALDH1A1KMT2ASMN1; SMN2MEN1KDM4E | |
| SCHEMBL15670569 | 0.74 | MMP1 (0.42) | MMP1MMP9MMP12ALDH1A1KMT2A | |
| SCHEMBL15670432 | 0.74 | MMP1 (0.42) | MMP1MMP9MMP12ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116576-A | Quinolizinone compound and preparation method thereof | 北京师范大学 | 2020-05-08 | — | — | CN | disclosed |