Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 12/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31188474 | 0.99 | KDM4E (0.42) | FKBP1AKDM4EMAPTMAPK1RECQL | |
| SCHEMBL6190090 | 0.84 | MEN1 (0.44) | FKBP1AKDM4EMAPTMAPK1RECQL | |
| SCHEMBL3425627 | 0.79 | PAOX (0.34) | KDM4EMAPTRECQL | |
| SCHEMBL5035064 | 0.79 | HDAC6 (0.32) | KDM4EMAPTRECQL | |
| SCHEMBL3428460 | 0.79 | PTGS1 (0.41) | KDM4EMAPK1CYP1A2MEN1RAB9A | |
| SCHEMBL20081691 | 0.78 | KDM4E (0.35) | KDM4EMAPTMAPK1RECQL | |
| SCHEMBL19675040 | 0.78 | HDAC6 (0.31) | KDM4EMAPTRECQL | |
| SCHEMBL19229985 | 0.75 | PLA2G7 (0.31) | — | |
| SCHEMBL5795312 | 0.74 | MAPT (0.49) | FKBP1AKDM4EMAPTMAPK1RECQL | |
| SCHEMBL19675107 | 0.73 | KDM4E (0.35) | KDM4EMAPTRECQLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4455667-B1 | DEVICE FOR DETECTING MOLECULES | VISCERA TECH LTD (GB) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024223672-A1 | DEVICE FOR DETECTING MOLECULES | VISCERA TECHNOLOGIES LTD (GB) | 2024-10-31 | — | — | WO | disclosed |
| EP-4455667-A1 | DEVICE FOR DETECTING MOLECULES | Viscera Technologies Ltd (GB) | 2024-10-30 | — | — | EP | disclosed |
| EP-1301790-B1 | DIRECT ASSESSMENT OF ANALYTE TO REFERENCE MOLECULE RATIOS | NASER WERNER DR (DE) | 2008-04-09 | — | — | EP | disclosed |
| US-20040038296-A1 | Direct assessment of analyte to reference molecule ratios | NASER, WERNER (DE) | 2004-02-26 | — | — | US | disclosed |
| EP-1301790-A2 | DIRECT ASSESSMENT OF ANALYTE TO REFERENCE MOLECULE RATIOS | Naser, Werner, Dr. (DE) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004950-A2 | DIRECT ASSESSMENT OF ANALYTE TO REFERENCE MOLECULE RATIOS | NASER WERNER (DE) | 2002-01-17 | — | — | WO | disclosed |