Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048757 | 0.88 | PPARG (0.44) | PPARGALDH1A1LMNAEPHX2L3MBTL1 | |
| SCHEMBL6023237 | 0.85 | EPHX2 (0.49) | PPARGALDH1A1EPHX2HPGDKDM4E | |
| SCHEMBL5044635 | 0.84 | PPARG (0.50) | PPARGALDH1A1LMNAEPHX2L3MBTL1 | |
| SCHEMBL5047489 | 0.81 | PPARG (0.42) | PPARGALDH1A1LMNAEPHX2L3MBTL1 | |
| SCHEMBL1860786 | 0.80 | PPARG (0.46) | PPARGALDH1A1LMNAEPHX2L3MBTL1 | |
| SCHEMBL5044609 | 0.78 | EPHX2 (0.52) | PPARGALDH1A1EPHX2HPGDKDM4E | |
| SCHEMBL5044608 | 0.77 | EPHX2 (0.49) | PPARGALDH1A1LMNAEPHX2HPGD | |
| SCHEMBL5044895 | 0.77 | EPHX2 (0.48) | PPARGALDH1A1EPHX2HPGDKDM4E | |
| SCHEMBL5047681 | 0.77 | DDR1 (0.43) | PPARGALDH1A1LMNAEPHX2HPGD | |
| SCHEMBL6023307 | 0.76 | HTR2C (0.44) | PPARGALDH1A1EPHX2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |