Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.34 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047584 | 0.83 | MEN1 (0.42) | MEN1HTTKMT2ASLC2A1CNR1 | |
| SCHEMBL5049002 | 0.77 | LTA4H (0.43) | THRATHRB | |
| SCHEMBL1854704 | 0.76 | SLC2A1 (0.57) | MEN1HTTKMT2ASLC2A1CNR1 | |
| SCHEMBL6717527 | 0.75 | SLC2A1 (0.42) | MEN1HTTKMT2ASLC2A1CNR1 | |
| SCHEMBL6717531 | 0.75 | ACHE (0.44) | MEN1HTTKMT2ASLC2A1CNR1 | |
| SCHEMBL1856357 | 0.74 | THRA (0.40) | MEN1HTTKMT2ASLC2A1CNR1 | |
| SCHEMBL27619411 | 0.74 | SLC2A1 (0.43) | MEN1HTTKMT2ASLC2A1CNR1 | |
| SCHEMBL23271677 | 0.72 | CNR1 (0.61) | MEN1HTTKMT2ASLC2A1CNR1 | |
| SCHEMBL29802382 | 0.72 | CNR1 (0.61) | MEN1HTTKMT2ASLC2A1CNR1 | |
| SCHEMBL23271675 | 0.72 | CNR1 (0.61) | MEN1HTTKMT2ASLC2A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |