Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 13/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5775051 | 0.92 | CRHR1 (0.41) | CRHR1 | |
| Trifluoroacetic Acid SCHEMBL5048824 | 0.88 | CRHR1 (0.40) | CRHR1 | |
| SCHEMBL5776895 | 0.86 | CRHR1 (0.36) | CRHR1 | |
| Trifluoroacetic Acid SCHEMBL5039148 | 0.85 | PKM (0.33) | CRHR1 | |
| Trifluoroacetic Acid SCHEMBL5048861 | 0.84 | MAPT (0.34) | CRHR1 | |
| Trifluoroacetic Acid SCHEMBL5043695 | 0.84 | HTT (0.34) | CRHR1 | |
| Trifluoroacetic Acid SCHEMBL5039802 | 0.84 | CACNA1B (0.34) | CRHR1 | |
| SCHEMBL5043842 | 0.84 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL5522193 | 0.83 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL5047507 | 0.79 | CRHR1 (0.38) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432283-B2 | Heterocyclic GABAA subtype selective receptor modulators | ROCHE PALO ALTO LLC (US) | 2008-10-07 | — | — | US | disclosed |