Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 3/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1854814 | 0.90 | TRPV1 (0.45) | TRPV1ALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL5047842 | 0.89 | TRPV1 (0.46) | TRPV1ALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL5040041 | 0.85 | NAAA (0.48) | HPGDLMNAL3MBTL1HDAC3HDAC1 | |
| SCHEMBL5044933 | 0.83 | LMNA (0.46) | TRPV1ALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL1857834 | 0.79 | TRPV1 (0.44) | TRPV1ALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL1855988 | 0.79 | TRPV1 (0.44) | TRPV1ALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL5044795 | 0.78 | MEN1 (0.45) | TRPV1HDAC3HDAC1HDAC2 | |
| SCHEMBL5047722 | 0.77 | TRPV1 (0.43) | TRPV1ALDH1A1HPGDLMNAHDAC3 | |
| SCHEMBL1856836 | 0.77 | NAAA (0.47) | LMNAL3MBTL1TMEM97SIGMAR1 | |
| SCHEMBL1854547 | 0.76 | MAPK14 (0.47) | TRPV1ALDH1A1HPGDLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-B1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | SERONO LAB (CH) | 2008-07-23 | — | — | EP | claimed |