SCHEMBL5044967

SCHEMBL5044967

Bc1cc(C2C(/C(N)=N/O)=C(N)Oc3c2ccc2ccccc32)cc(OC)c1OC

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MYB P10242 17/20 0.59
ACHE P22303 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4538391 0.90 MYB (0.59) MYBACHE
SCHEMBL6014324 0.90 MYB (0.59) MYBACHE
SCHEMBL5044999 0.85 MYB (0.51) MYBACHE
SCHEMBL5044963 0.81 MYB (0.89) MYB
SCHEMBL15370260 0.76 MYB (0.54) MYBACHE
SCHEMBL6014836 0.76 MYB (0.54) MYBACHE
SCHEMBL4538386 0.76 MYB (0.59) MYBACHE
SCHEMBL4335346 0.74 MYB (1.00) MYB
SCHEMBL5044919 0.73 MYB (0.63) MYB
SCHEMBL20368759 0.71 MYB (0.90) MYB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012062901-A2 CHROMENE DERIVATIVES AND THEIR ANALOGA AS WNT PATHWAY ANTAGONISTS DEUTSCHES KREBSFORSCHUNGSZENTRUM (DKFZ) (DE) 2012-05-18 WO disclosed
WO-2012062905-A2 CHROMENE DERIVATIVES AND THEIR ANALOGA AS WNT PATHWAY ANTAGONISTS DEUTSCHES KREBSFORSCHUNGSZENTRUM (DKFZ) (DE) 2012-05-18 WO disclosed