Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYB | P10242 | 17/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541509 | 0.91 | MYB (0.57) | MYBACHE | |
| SCHEMBL4561271 | 0.82 | MYB (0.58) | MYBACHE | |
| SCHEMBL5044963 | 0.77 | MYB (0.89) | MYB | |
| SCHEMBL5044967 | 0.76 | MYB (0.59) | MYBACHE | |
| SCHEMBL5044999 | 0.73 | MYB (0.51) | MYBACHEMEN1MAPTCYP2C9 | |
| SCHEMBL4335346 | 0.71 | MYB (1.00) | MYB | |
| SCHEMBL4537494 | 0.70 | MYB (0.55) | MYBACHE | |
| SCHEMBL20368759 | 0.69 | MYB (0.90) | MYB | |
| SCHEMBL4331540 | 0.68 | MYB (0.87) | MYB | |
| SCHEMBL6014324 | 0.66 | MYB (0.59) | MYBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062901-A2 | CHROMENE DERIVATIVES AND THEIR ANALOGA AS WNT PATHWAY ANTAGONISTS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DKFZ) (DE) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062905-A2 | CHROMENE DERIVATIVES AND THEIR ANALOGA AS WNT PATHWAY ANTAGONISTS | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DKFZ) (DE) | 2012-05-18 | — | — | WO | disclosed |