SCHEMBL504512

SCHEMBL504512

CCCC[SiH](OCC)C(C)CCSSSSCCC(C)[SiH](CCCC)OCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL106536 0.74
SCHEMBL2561183 0.68
SCHEMBL9157727 0.64
SCHEMBL28044458 0.62
SCHEMBL29023311 0.61
SCHEMBL8845573 0.61
SCHEMBL10397988 0.61
SCHEMBL2089669 0.60 OPRM1 (0.37)
SCHEMBL15914572 0.60 ALDH1A1 (0.30)
SCHEMBL28449699 0.60 DNM1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 540 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11858821-B2 Method of silica pretreatment THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-01-02 US claimed
EP-4023724-A2 METHOD OF MAKING HYDROPHOBATED SILICA AND USE OF SUCH A SILICA The Goodyear Tire & Rubber Company (US) 2022-07-06 EP claimed
US-20220204351-A1 METHOD OF SILICA PRETREATMENT GOODYEAR TIRE & RUBBER COMPANY, THE 2022-06-30 US claimed
US-20040034150-A1 Rubber compositions and method for increasing the mooney scorch value UNIROYAL CHEMICAL COMPANY, INC. 2004-02-19 US claimed
US-6620875-B2 Silica filler, coupling agent, cure-enhancing polyoxyalkylene oxide and high molecular weight thiuram disulfide; carbon black; ozone and oxidation resistance; tire treads UNIROYAL CHEMICAL COMPANY, INC. 2003-09-16 US claimed
US-20030119960-A1 Rubber compositions and method for decreasing the tangent delta value UNIROYAL CHEMICAL COMPANY, INC. 2003-06-26 US claimed
US-20030119995-A1 Silica filler, coupling agent, cure-enhancing polyoxyalkylene oxide and high molecular weight thiuram disulfide; carbon black; ozone and oxidation resistance; tire treads ADDIVANT USA, LLC 2003-06-26 US claimed
US-6465670-B2 SURFACE TREATMENT USING ORGANOSILICON COMPOUND, SOLVENT AND PHASE TRANSFER CATALYST THE GOODYEAR TIRE & RUBBER COMPANY 2002-10-15 US claimed
US-6390163-B1 BUTADIENE OR ISOPRENE-STYRENE COPOLYMER THE GOODYEAR TIRE & RUBBER COMPANY 2002-05-21 US claimed
US-20020022085-A1 Preparation of surface modified silica GOODYEAR TIRE & RUBBER COMPANY, THE 2002-02-21 US claimed
US-6053226-A BLENDING A DIENE BASED ELASTOMER, A REINFROCEMENT FILLER COMPRISED OF PRECIPITATED SILICA AND CARBON BLACK, A PREFORMED COMPOSITE OF MICROCRYSTALLINE WAX, SILICA COUPLING AGENT, ANTIDEGRADANT, VULCANIZATION PROMOTER AND CARBON BLACK THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-04-25 US claimed
EP-0764688-B1 High performance blend for tire treads GOODYEAR TIRE & RUBBER (US) 2000-02-23 EP claimed
EP-0764688-A1 High performance blend for tire treads THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-03-26 EP claimed
US-5534592-A POLYBUTADIENE RUBBER BLEND THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-07-09 US claimed
US-12043735-B2 Resin modified oil extended rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-07-23 US disclosed
US-20240228756-A1 RUBBER TIRE COMPOUND CONTAINING IPN-PROMOTING RESIN THE GOODYEAR TIRE & RUBBER COMPANY 2024-07-11 US disclosed
US-11970618-B2 Rubber tire compound containing IPN-promoting resin THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-04-30 US disclosed
US-4229333-A IN ABSENCE OF ELEMENTAL SULFUR DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-10-21 US disclosed
US-3957718-A Compositions containing silica, a phenoplast or an aminoplast, and a silane DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-05-18 US disclosed
US-3938574-A Vulcanizable rubber mixture for tire treads having improved skid resistance DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1976-02-17 US disclosed