Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15215895 | 0.85 | POLB (0.49) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL21785057 | 0.82 | OPRM1 (0.49) | ALDH1A1GLATSHRSMN1; SMN2KDM4E | |
| SCHEMBL5045325 | 0.82 | ALDH1A1 (0.46) | ALDH1A1GLATSHRSMN1; SMN2KDM4E | |
| SCHEMBL10926482 | 0.82 | ALDH1A1 (0.48) | ALDH1A1GLATSHRSMN1; SMN2MEN1 | |
| SCHEMBL10282142 | 0.82 | ALDH1A1 (0.48) | ALDH1A1GLATSHRSMN1; SMN2MEN1 | |
| SCHEMBL8443789 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1GLATSHRSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL28795770 | 0.81 | ALDH1A1 (0.44) | ALDH1A1GLATSHRSMN1; SMN2KDM4E | |
| SCHEMBL14248561 | 0.81 | ACHE (0.44) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL6684816 | 0.80 | MAPT (0.53) | ALDH1A1GLATSHRSMN1; SMN2KDM4E | |
| SCHEMBL8342856 | 0.80 | ALDH1A1 (0.47) | ALDH1A1GLATSHRSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020042618-A1 | MULTI-SUBSTITUTED PYRIDONE DERIVATIVES AND MEDICAL USE THEREOF | 北京越之康泰生物医药科技有限公司 | 2020-03-05 | — | — | WO | disclosed |
| EP-1651643-A4 | BICYCLIC COMPOUNDS AND COMPOSITIONS AS PDF INHIBITORS | IRM LLC (BM) | 2008-10-08 | — | — | EP | disclosed |
| EP-1651643-A2 | BICYCLIC COMPOUNDS AND COMPOSITIONS AS PDF INHIBITORS | IRM, LLC (BM) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005011611-A2 | BICYCLIC COMPOUNDS AND COMPOSITIONS AS PDF INHIBITORS | IRM, LLC (BM) | 2005-02-10 | — | — | WO | disclosed |