Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430450 | 0.83 | LMNA (0.38) | — | |
| SCHEMBL4509470 | 0.72 | LMNA (0.36) | — | |
| SCHEMBL5048110 | 0.70 | KAT2A (0.30) | — | |
| SCHEMBL12052217 | 0.67 | LMNA (0.40) | — | |
| SCHEMBL18844857 | 0.65 | BRD4 (0.35) | — | |
| SCHEMBL5045298 | 0.63 | CYP1A2 (0.32) | — | |
| SCHEMBL5049184 | 0.62 | ACE (0.32) | — | |
| SCHEMBL10164152 | 0.57 | LMNA (0.48) | TP53MDM2 | |
| SCHEMBL28605644 | 0.57 | ACE (0.36) | — | |
| SCHEMBL30381336 | 0.57 | ACE (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993998-A1 | 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES | UCB Pharma, S.A. (BE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007065634-A1 | 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES | UCB PHARMA, S.A. (BE) | 2007-06-14 | — | — | WO | disclosed |