Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.43 |
| ▸ | CTSS | P25774 | 10/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13723330 | 0.92 | CTSK (0.40) | CTSKCTSSCTSLCTSBGSTP1 | |
| SCHEMBL14190234 | 0.87 | CTSS (0.47) | CTSKCTSSCTSLCTSB | |
| SCHEMBL13722720 | 0.82 | CTSS (0.44) | CTSKCTSSCTSLCTSB | |
| SCHEMBL23059046 | 0.80 | CTSK (0.60) | CTSKCTSSCTSLCTSBCYP1A2 | |
| SCHEMBL2367071 | 0.80 | KLK5 (0.48) | CTSKCTSSCTSLCTSBKLK5 | |
| SCHEMBL27683505 | 0.80 | KLK5 (0.48) | CTSKCTSSCTSLCTSBKLK5 | |
| SCHEMBL13323781 | 0.80 | KLK5 (0.48) | CTSKCTSSCTSLCTSBKLK5 | |
| SCHEMBL903742 | 0.80 | CTSK (0.48) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL2367381 | 0.80 | CTSK (0.48) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL2367189 | 0.80 | CTSK (0.48) | CTSKCTSSCTSLCTSBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368424-B2 | Acylated nonadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2008-05-06 | — | — | US | disclosed |
| US-7368424-B2 | Acylated nonadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2008-05-06 | — | — | US | disclosed |