Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15195141 | 0.84 | SMN1; SMN2 (0.62) | DDAH1ADRA2CSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL5020552 | 0.82 | DDAH1 (0.71) | DDAH1ADRA2CSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL29751905 | 0.79 | DDAH1 (0.67) | DDAH1ADRA2CSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL423424 | 0.79 | DDAH1 (0.67) | DDAH1ADRA2CSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL10533720 | 0.79 | DDAH1 (0.61) | DDAH1ADRA2CSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9531515 | 0.79 | DDAH1 (0.71) | DDAH1ADRA2CSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL9388714 | 0.79 | DDAH1 (0.76) | DDAH1ADRA2CSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL8409996 | 0.79 | DDAH1 (0.71) | DDAH1ADRA2CSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL3034413 | 0.79 | DDAH1 (0.71) | DDAH1ADRA2CSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL774784 | 0.78 | DDAH1 (0.65) | DDAH1ADRA2CSMN1; SMN2KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173688-B2 | Thiazole compounds, and compositions and methods using same | NEXMED HOLDINGS, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-20090311343-A1 | Thiazole Compounds, and Compositions and Methods Using Same | NEXMED HOLDINGS, INC. | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090311343-A1 | Thiazole Compounds, and Compositions and Methods Using Same | RCC2, PKD1, REN | DDAH1 1680/4885ADRA2C 3313/4885SMN1; SMN2 4584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.