Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDAH1 | O94760 | 1/20 | 0.71 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL423424 | 0.90 | DDAH1 (0.67) | DDAH1ADRA2CKMT2AMEN1MAPT | |
| SCHEMBL29751905 | 0.90 | DDAH1 (0.67) | DDAH1ADRA2CKMT2AMEN1MAPT | |
| SCHEMBL11345934 | 0.89 | DDAH1 (0.65) | DDAH1ADRA2CKMT2AMEN1MAPT | |
| SCHEMBL11779882 | 0.87 | DDAH1 (0.63) | DDAH1ADRA2CKMT2AMEN1MAPT | |
| SCHEMBL774784 | 0.86 | DDAH1 (0.65) | DDAH1ADRA2CKMT2AMEN1MAPT | |
| SCHEMBL9531515 | 0.83 | DDAH1 (0.71) | DDAH1ADRA2CKMT2AMEN1MAPT | |
| SCHEMBL9388714 | 0.83 | DDAH1 (0.76) | DDAH1ADRA2CKMT2AMEN1MAPT | |
| SCHEMBL8409996 | 0.83 | DDAH1 (0.71) | DDAH1ADRA2CKMT2AMEN1MAPT | |
| SCHEMBL3034413 | 0.83 | DDAH1 (0.71) | DDAH1ADRA2CKMT2AMEN1MAPT | |
| SCHEMBL5046080 | 0.82 | DDAH1 (0.65) | DDAH1ADRA2CKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210228550-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2021-07-29 | — | — | US | disclosed |
| US-10945996-B2 | Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2021-03-16 | — | — | US | disclosed |
| US-20190209531-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2019-07-11 | — | — | US | disclosed |
| US-20180000793-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | ABEL-SANTOS ERNESTO (US) | 2018-01-04 | — | — | US | disclosed |
| WO-2016127102-A2 | INHIBITING GERMINATION OF CLOSTRIDIUM PERFRINGENS SPORES TO REDUCE NECROTIC ENTERITIS | ABEL-SANTOS ERNESTO (US) | 2016-08-11 | — | — | WO | disclosed |
| US-20120269902-A1 | Thiazole Compounds, and Compositions and Methods Using Same | NEXMED HOLDINGS, INC. | 2012-10-25 | — | — | US | disclosed |
| US-8173688-B2 | Thiazole compounds, and compositions and methods using same | NEXMED HOLDINGS, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| US-20090311343-A1 | Thiazole Compounds, and Compositions and Methods Using Same | NEXMED HOLDINGS, INC. | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120269902-A1 | Thiazole Compounds, and Compositions and Methods Using Same | RCC2, PKD1, REN | DDAH1 1680/4885ADRA2C 3313/4885KMT2A 1791/4885 |
| US-10945996-B2 | Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis | CASP3, SI, PYCARD | DDAH1 2270/4885ADRA2C 4119/4885KMT2A 4855/4885 |
| US-20190209531-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | CASP3, SI, PYCARD | DDAH1 2270/4885ADRA2C 4119/4885KMT2A 4855/4885 |
| US-20210228550-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | CASP3, SI, PYCARD | DDAH1 2270/4885ADRA2C 4119/4885KMT2A 4855/4885 |
| US-20180000793-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | CASP3, SI, PYCARD | DDAH1 2270/4885ADRA2C 4119/4885KMT2A 4855/4885 |
| US-20090311343-A1 | Thiazole Compounds, and Compositions and Methods Using Same | RCC2, PKD1, REN | DDAH1 1680/4885ADRA2C 3313/4885KMT2A 1791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.