Acetone

Acetone

SCHEMBL504609

CC(=O)CC=CC(=O)NCO.CC(C)=O

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32
CNR1 P21554 3/20 0.31
CNR2 P34972 3/20 0.31
ALDH1A1 P00352 1/20 0.31
TRPA1 O75762 1/20 0.30
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL11143338 0.79 MGAM (0.31)
SCHEMBL12328435 0.76 CHRNB2 (0.52) CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL11349206 0.75 CNR2 (0.42) CNR1CNR2TRPA1TRPV1
SCHEMBL810691 0.75 ALDH1A1 (0.36) CNR1CNR2ALDH1A1
SCHEMBL866792 0.74 ALDH1A1 (0.39) ALDH1A1
SCHEMBL866793 0.74 ALDH1A1 (0.39) ALDH1A1
SCHEMBL867285 0.74 ALDH1A1 (0.39) ALDH1A1
SCHEMBL6854552 0.72 TAS1R3 (0.53) CNR1CNR2TRPA1TRPV1
SCHEMBL820926 0.70
SCHEMBL11100545 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2484703-B1 Polymeric compositions comprising at least one volume excluding polymer JOHNSON & JOHNSON VISION CARE (US) 2015-03-25 EP claimed
EP-1918310-B1 Polymeric compositions comprising at least one volume excluding polymer JOHNSON & JOHNSON VISION CARE (US) 2014-01-22 EP claimed
US-20120024787-A1 Novel Coated Membranes and Other Articles MILLIPORE CORPORATION (US) 2012-02-02 US claimed
US-20100065498-A1 Novel Coated Membranes and Other Articles MILLIPORE CORPORATION (US) 2010-03-18 US claimed
EP-1779922-A1 Novel coated membranes and other articles MILLIPORE CORPORATION (US) 2007-05-02 EP claimed
EP-1381447-A1 COATED MEMBRANES MILLIPORE CORPORATION (US) 2004-01-21 EP claimed
EP-1077952-B1 POLYMERIZABLE HYDROPHILIC ULTRAVIOLET LIGHT ABSORBING MONOMERS PHARMACIA & UPJOHN BV (NL) 2003-11-12 EP claimed
EP-0889916-B1 HIGH REFRACTIVE INDEX HYDROGELS PREPARED FROM POLYMERS AND COPOLYMERS OF N-BENZYL-N-METHYLACRYLAMIDE UPJOHN CO (US) 2003-05-07 EP claimed
US-20030077435-A1 Novel coated membranes and other articles EMD MILLIPORE CORPORATION 2003-04-24 US claimed
WO-2002087734-A1 NOVEL COATED MEMBRANES AND OTHER ARTICLES MILLIPORE CORPORATION (US) 2002-11-07 WO claimed
US-6036891-A 2-(2'-HYDROXY-5'-(METH)ACRYLOXYALKOXYALKYLPHENYL)-2H-BENZOTRIAZOLE MONOMERS WHICH FORM OPTICALLY CLEAR ULTRAVIOLET LIGHT ABSORBING HYDROGELS USEFUL IN INTRAOCULAR LENSES, CONTACT LENSES PHARMACIA & UPJOHN (US) 2000-03-14 US claimed
WO-1999058507-A1 POLYMERIZABLE HYDROPHILIC ULTRAVIOLET LIGHT ABSORBING MONOMERS PHARMACIA & UPJOHN GRONINGEN B.V. (NL) 1999-11-18 WO claimed
EP-0889916-A1 HIGH REFRACTIVE INDEX HYDROGELS PREPARED FROM POLYMERS AND COPOLYMERS OF N-BENZYL-N-METHYLACRYLAMIDE Pharmacia Iovision Inc. (US) 1999-01-13 EP claimed
US-5717049-A INTRAOCULAR LENSES PHARMACIA IOVISION, INC. (US) 1998-02-10 US claimed
WO-1997035896-A1 HIGH REFRACTIVE INDEX HYDROGELS PREPARED FROM POLYMERS AND COPOLYMERS OF N-BENZYL-N-METHYLACRYLAMIDE PHARMACIA IOVISION INC. (US) 1997-10-02 WO claimed
EP-0544933-B1 A pressure sensitive adhesive composition and a pressure sensitive adhesive sheet, a label and a laminate utilizing it LINTEC CORP (JP) 1996-02-07 EP claimed
US-5389437-A Paper or synthetic resin film coated with adhesive having improved blister resistance, removability, cohesive strength, heat resistance, corrosion resistance SAIDEN CHEMICAL INDUSTRY CO., LTD. (JP) 1995-02-14 US claimed
US-5278271-A Acrylic copolymer comprising aminoalkyl (meth)acrylamide SAIDEN CHEMICAL INDUSTRY CO., LTD. (JP) 1994-01-11 US claimed
EP-0544933-A1 A pressure sensitive adhesive composition and a pressure sensitive adhesive sheet, a label and a laminate utilizing it LINTEC Corporation (JP) 1993-06-09 EP claimed
EP-0057906-B1 COATING COMPOSITION AND PROCESS FOR PREPARING SYNTHETIC RESIN SHAPED ARTICLES BY USING SAME MITSUBISHI RAYON CO., LTD. (JP) 1985-05-29 EP claimed