Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA4 | P22748 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099109 | 0.81 | MAPT (0.68) | CA12CA1CA2CA4CA9 | |
| SCHEMBL3026943 | 0.79 | CA12 (0.59) | CA12CA1CA2CA4CA9 | |
| SCHEMBL9517976 | 0.78 | ELANE (0.59) | MAPTL3MBTL1PKMLMNAGAA | |
| SCHEMBL8350895 | 0.78 | TP53 (0.56) | L3MBTL1LMNAGAA | |
| SCHEMBL3104512 | 0.78 | MAPT (0.68) | CA12CA1CA2CA4CA9 | |
| SCHEMBL16599337 | 0.78 | MAPT (0.47) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5267194 | 0.77 | PTGS2 (0.57) | CA12CA1CA2CA4CA9 | |
| SCHEMBL2762835 | 0.77 | CA12 (0.56) | CA12CA1CA2CA4CA9 | |
| SCHEMBL3093420 | 0.77 | MAPT (0.67) | CA12CA1CA2CA4CA9 | |
| SCHEMBL15941568 | 0.76 | TP53 (0.59) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951653-A1 | SALICYLIC ACID DERIVATIVES | NicOx S.A. (FR) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007060112-A1 | SALICYLIC ACID DERIVATIVES | NICOX S.A. (FR) | 2007-05-31 | — | — | WO | disclosed |